HEADER RECORD*******LIBRARY HEADER RECORD!!!!!!!000000000000000000000000000000 SAS SAS SASLIB 9.4 Linux 18NOV21:22:15:3218NOV21:22:15:32 HEADER RECORD*******MEMBER HEADER RECORD!!!!!!!000000000000000001600000000140 HEADER RECORD*******DSCRPTR HEADER RECORD!!!!!!!000000000000000000000000000000 SAS ADDS SASDATA 9.4 Linux 18NOV21:22:15:3218NOV21:22:15:32 HEADER RECORD*******NAMESTR HEADER RECORD!!!!!!!000000010200000000000000000000 STUDYID Study Identifier USUBJID Unique Subject Identifier SUBJID Subject Identifier for the Study SITEID Study Site Identifier &ADT Analysis Date DATE *ASTDT Analysis Start Date DATE 2ASTDY Analysis Start Relative Day :DSPHASE Disposition Phase B DSPHASENDisposition Phase Code (N) V DSCAT Category for Disposition Event ^$ DSDECOD Standardized Disposition Term o DSDECODNStandardized Disposition Term (N) d DSTERM Reported Term for the Disposition Event M1PD2DT 1 Month Post Dose 2 Visit Date DATE M6PD2DT 6 Months Post Dose 2 Visit Date DATE M1PX2DT 1 Month Post Dose 4 Visit Date DATE M1P2CUT 1 Month PD2 Cutoff Date for Disposition DATE M1P2EXC Excluded from 1 Month Post Dose 2 AGE Age  AGEU Age Units (SEX Sex -SEXN Sex (N) .)RACE Race 6RACEN Race (N) _)ARACE Analysis Race gARACEN Analysis Race (N) RANDFL Randomized Population Flag SAFFL Safety Population Flag ARM Description of Planned Arm  ARMCD Planned Arm Code ACTARM Description of Actual Arm  ACTARMCDActual Arm Code !TRTSDT Date of First Exposure to Treatment DATE "TRTSTM Time of First Exposure to Treatment TIME  #TRTSDTM Datetime of First Exposure to Treatment DATETIME $TRTEDT Date of Last Exposure to Treatment DATE %TRTETM Time of Last Exposure to Treatment TIME  &TRTEDTM Datetime of Last Exposure to Treatment DATETIME  &'TRTSEQP Planned Sequence of Treatments &(TRTSEQA Actual Sequence of Treatments 8 )AGEGR1 Pooled Age Group 1 ^*AGEGR1N Pooled Age Group 1 (N) i+COHORT Cohort Group q,COHORTN Cohort Group (N) r-DOSALVL Actual Dosing Level z.DOSALVLNActual Dosing Level (N) {/DOSPLVL Planned Dosing Level 0DOSPLVLNPlanned Dosing Level (N) 1VAX101DTVaccination Date 01 DATE 2VAX102DTVaccination Date 02 DATE 3VAX10UDTVaccination Date Unplanned DATE 4VAX201DTVaccination Date 03 DATE 5VAX202DTVaccination Date 04 DATE 6VAX20UDTVaccination Date Unplanned in Period 02 DATE 7UNBLNDDTTreatment Unblinded Date DATE $8VAX101 Vaccination 01 $9VAX102 Vaccination 02 $:VAX10U Vaccination Unplanned  $;VAX201 Vaccination 03 0$TRT01A Actual Treatment for Period 01 y?TRT01AN Actual Treatment for Period 01 (N) @TRT02A Actual Treatment for Period 02 ATRT02AN Actual Treatment for Period 02 (N) BTRT01P Planned Treatment for Period 01 CTRT01PN Planned Treatment for Period 01 (N) DTRT02P Planned Treatment for Period 02 ETRT02PN Planned Treatment for Period 02 (N) FTR01SDT Date of First Exposure in Period 01 DATE GTR01STM Time of First Exposure in Period 01 TIME   HTR01SDTMDatetime of First Exposure in Period 01 DATETIME ITR01EDT Date of Last Exposure in Period 01 DATE JTR01ETM Time of Last Exposure in Period 01 TIME  %KTR01EDTMDatetime of Last Exposure in Period 01 DATETIME -LTR02SDT Date of First Exposure in Period 02 DATE 5MTR02STM Time of First Exposure in Period 02 TIME  =NTR02SDTMDatetime of First Exposure in Period 02 DATETIME EOTR02EDT Date of Last Exposure in Period 02 DATE MPTR02ETM Time of Last Exposure in Period 02 TIME  UQTR02EDTMDatetime of Last Exposure in Period 02 DATETIME ]RPHASE Study Phase eSPHASEN Study Phase (N) lTEOSDCDT End Of Study Discontinuation Date DATE tUEOTDCDT End Of Treatment Discontinuation Date DATE |VBLDV6DT Blood Sample Date 1 Month after Vax 2 DATE WBLDV7DT Blood Sample Date 6 Months after Vax 2 DATE  XAGEGR4 Pooled Age Group 4 YAGEGR4N Pooled Age Group 4 (N) ZPEDIMMFLPop for Non-inferiority Assessement [PEDREAFLPhase 2/3 Pop for 12-25 Reacto Subset \HIVFL HIV Positive Subjects Flag ]DS3KFL FU to 6MPD2 ^EOTXDCDTEnd Of Open Label Treatment D/C Date DATE _EOTXDCRSEnd Of Open Label Treatment D/C Reason `BDCSRDT Double Blinded Follow-up Censor Date DATE aX1CSRDT Crossover Dose1 Censor Date DATE bSTCSRDT Study Censor Date DATE cAGETR01 Age at Vaccination 01 dAGETRU01Age Units at Vaccination 01 eDOMAIN Domain Abbreviation fDSSEQ Sequence Number  HEADER RECORD*******OBS HEADER RECORD!!!!!!!000000000000000000000000000000 C4591001C4591001 1005 10051317100513171005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr^DVDHr|xBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr^DVDHr|x......Phase 3A@..DVDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051317100513171005.DVB9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr^DVDHr|xBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr^DVDHr|x......Phase 3A@..DVDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051328100513281005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr^DVDHr{BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr^DVDHr{......Phase 3A@..DVDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051328100513281005.DVB5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr^DVDHr{BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr^DVDHr{......Phase 3A@..DVDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051339100513391005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr`DWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr`DVDHr{DWDHsr|pDWDLHsLPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051339100513391005.DVB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr`DWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr`DVDHr{DWDHsr|pDWDLHsLPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051339100513391005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr`DWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr`DVDHr{DWDHsr|pDWDLHsLPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051339100513391005.DWC@OPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDVYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr`DWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr`DVDHr{DWDHsr|pDWDLHsLPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051410100514101005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDdHrdDWDҴHsu4DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051410100514101005.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDdHrdDWDҴHsu4DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051410100514101005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDdHrdDWDҴHsu4DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051410100514101005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDdHrdDWDҴHsu4DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051412100514121005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr,DW DHr& BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr,DW DHr& ......Phase 3A@..DW0DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051412100514121005.DW0B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr,DW DHr& BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr,DW DHr& ......Phase 3A@..DW0DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051413100514131005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr(DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWcBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr(DW DHr......Phase 3A@DW.DW(DW12-15 YearsA YNY. DWbDWDWAYEARSDSAC4591001C4591001 1005 10051413100514131005.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr(DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWcBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr(DW DHr......Phase 3A@DW.DW(DW12-15 YearsA YNY. DWbDWDWAYEARSDSA C4591001C4591001 1005 10051413100514131005.DWBFOLLOW-UP BDISPOSITION EVENTOTHER ApParticipant enrolled in C4591031 DW(DW.DW(YAYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr(DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWcBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr(DW DHr......Phase 3A@DW.DW(DW12-15 YearsA YNY. DWbDWDWAYEARSDSAPC4591001C4591001 1005 10051414100514141005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD HrEDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD HrEDW DHrDWDHs}"tDWDHsPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051414100514141005.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD HrEDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD HrEDW DHrDWDHs}"tDWDHsPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051414100514141005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD HrEDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD HrEDW DHrDWDHs}"tDWDHsPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051414100514141005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD HrEDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD HrEDW DHrDWDHs}"tDWDHsPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051415100514151005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDڬHs(,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW DHr/DWDtHsvetDWDڬHs(,Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051415100514151005.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDڬHs(,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW DHr/DWDtHsvetDWDڬHs(,Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051415100514151005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDڬHs(,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW DHr/DWDtHsvetDWDڬHs(,Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051415100514151005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDڬHs(,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW DHr/DWDtHsvetDWDڬHs(,Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051417100514171005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsFPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrŅDWDHsƶxDWD HsFPhase 3A@..DW1DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051417100514171005.DW1B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsFPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrŅDWDHsƶxDWD HsFPhase 3A@..DW1DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051417100514171005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsFPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrŅDWDHsƶxDWD HsFPhase 3A@..DW1DW12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051418100514181005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWDHrņBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWDHrņ......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051418100514181005.DW1B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWDHrņBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWDHrņ......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051419100514191005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWpDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr%DWTD(Hs"(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DW?DWT.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr%DW DHrDW?DHsf\DWTD(Hs"(Phase 3A@..DW(.12-15 YearsAYYNN. DW5DWDWAYEARSDSAC4591001C4591001 1005 10051419100514191005.DW(B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWpDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr%DWTD(Hs"(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DW?DWT.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr%DW DHrDW?DHsf\DWTD(Hs"(Phase 3A@..DW(.12-15 YearsAYYNN. DW5DWDWAYEARSDSA C4591001C4591001 1005 10051419100514191005DW?DW?BGREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWpDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr%DWTD(Hs"(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DW?DWT.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr%DW DHrDW?DHsf\DWTD(Hs"(Phase 3A@..DW(.12-15 YearsAYYNN. DW5DWDWAYEARSDSA0C4591001C4591001 1005 10051419100514191005.DWpBxOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWpDW(YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDLHr%DWTD(Hs"(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DW?DWT.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDLHr%DW DHrDW?DHsf\DWTD(Hs"(Phase 3A@..DW(.12-15 YearsAYYNN. DW5DWDWAYEARSDSA@C4591001C4591001 1005 10051420100514201005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDިHr$(DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDިHr$(DW DHr......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051420100514201005.DW(B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDިHr$(DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDިHr$(DW DHr......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051421100514211005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVD0Hru0DWDӤHsϤPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0Hru0DWD$Hr!DWD Hss DWDӤHsϤPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051421100514211005.DW/B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVD0Hru0DWDӤHsϤPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0Hru0DWD$Hr!DWD Hss DWDӤHsϤPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051421100514211005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVD0Hru0DWDӤHsϤPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0Hru0DWD$Hr!DWD Hss DWDӤHsϤPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051421100514211005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/YAYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVD0Hru0DWDӤHsϤPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0Hru0DWD$Hr!DWD Hss DWDӤHsϤPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051422100514221005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDHrwDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrwDWDHr"XDWDHHssHDWDhHshPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051422100514221005.DW/B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDHrwDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrwDWDHr"XDWDHHssHDWDhHshPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051422100514221005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDHrwDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrwDWDHr"XDWDHHssHDWDhHshPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051422100514221005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/YAYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDHrwDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrwDWDHr"XDWDHHssHDWDhHshPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051424100514241005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW3DW.DW3 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHroDWDDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHroDWDDHrD......Phase 3A@..DW3DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051424100514241005.DW3B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW3DW.DW3 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHroDWDDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHroDWDDHrD......Phase 3A@..DW3DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051425100514251005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrLDWDHrCBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrLDWDHrC......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051425100514251005.DW0B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrLDWDHrCBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrLDWDHrC......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051427100514271005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDDHrzDDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDDHrzDDWDHr%PDWD@HsrYDWDHsPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051427100514271005.DW/B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDDHrzDDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDDHrzDDWDHr%PDWD@HsrYDWDHsPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051427100514271005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDDHrzDDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDDHrzDDWDHr%PDWD@HsrYDWDHsPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051427100514271005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDDHrzDDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDDHrzDDWDHr%PDWD@HsrYDWDHsPhase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051428100514281005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD͌HrDWD|HrβBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD͌HrDWD|Hrβ......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051428100514281005.DW1B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD͌HrDWD|HrβBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD͌HrDWD|Hrβ......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051429100514291005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr DWDHrq@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr DWDHrq@......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051429100514291005.DW6B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr DWDHrq@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr DWDHrq@......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051430100514301005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD{Hr@DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWxDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD{Hr@DWD4Hrm4DWxDHsQ<DWDHslPhase 3A@..DW0.12-15 YearsA YNN. DWtDWDWAYEARSDSAC4591001C4591001 1005 10051430100514301005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD{Hr@DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWxDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD{Hr@DWD4Hrm4DWxDHsQ<DWDHslPhase 3A@..DW0.12-15 YearsA YNN. DWtDWDWAYEARSDSA C4591001C4591001 1005 10051430100514301005DWxDWxBzREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD{Hr@DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWxDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD{Hr@DWD4Hrm4DWxDHsQ<DWDHslPhase 3A@..DW0.12-15 YearsA YNN. DWtDWDWAYEARSDSA0C4591001C4591001 1005 10051430100514301005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD{Hr@DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWxDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD{Hr@DWD4Hrm4DWxDHsQ<DWDHslPhase 3A@..DW0.12-15 YearsA YNN. DWtDWDWAYEARSDSA@C4591001C4591001 1005 10051431100514311005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWDHr̈́BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWDHr̈́......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051431100514311005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWDHr̈́BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWDHr̈́......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051436100514361005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrXDWDʼHrͨBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrXDWDʼHrͨ......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051436100514361005.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrXDWDʼHrͨBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrXDWDʼHrͨ......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051437100514371005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWDHrͨDWD@HsjDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051437100514371005.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWDHrͨDWD@HsjDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051437100514371005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWDHrͨDWD@HsjDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051437100514371005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWDHrͨDWD@HsjDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051438100514381005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrLDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrLDWD͌HrͫDWDHsjHDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051438100514381005.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrLDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrLDWD͌HrͫDWDHsjHDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051438100514381005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrLDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrLDWD͌HrͫDWDHsjHDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051438100514381005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrLDWDHs!Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrLDWD͌HrͫDWDHsjHDWDHs!Phase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051439100514391005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDԔHrDWDHrb|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDԔHrDWDHrb|......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051439100514391005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDԔHrDWDHrb|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDԔHrDWDHrb|......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051440100514401005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHrDWD HraDWDHst<DWDhHshPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051440100514401005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHrDWD HraDWDHst<DWDhHshPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051440100514401005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHrDWD HraDWDHst<DWDhHshPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051440100514401005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHrDWD HraDWDHst<DWDhHshPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051441100514411005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWD(Hrͦ(BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWD(Hrͦ(......Phase 3A@DW.DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051441100514411005.DW1B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWD(Hrͦ(BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWD(Hrͦ(......Phase 3A@DW.DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051441100514411005.DWBFOLLOW-UP BDISPOSITION EVENTOTHER ApParticipant enrolled in C4591031 DW1DW.DW1YAYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWD(Hrͦ(BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWD(Hrͦ(......Phase 3A@DW.DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAPC4591001C4591001 1005 10051444100514441005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrDWD0Hs~@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrDWDHrͷDWDHsvtDWD0Hs~@Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051444100514441005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrDWD0Hs~@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrDWDHrͷDWDHsvtDWD0Hs~@Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051444100514441005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrDWD0Hs~@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrDWDHrͷDWDHsvtDWD0Hs~@Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051444100514441005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrDWD0Hs~@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrDWDHrͷDWDHsvtDWD0Hs~@Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051445100514451005DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr8DWD~HsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr8DWDTHrzTDWDHs~DWD~HsLPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051445100514451005.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr8DWD~HsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr8DWDTHrzTDWDHs~DWD~HsLPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051445100514451005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr8DWD~HsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr8DWDTHrzTDWDHs~DWD~HsLPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051445100514451005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr8DWD~HsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr8DWDTHrzTDWDHs~DWD~HsLPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051447100514471005DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDDW.DWD AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr$`DW(DDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW(....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr$`DW(DDHrD......Phase 3A@..DWDDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051447100514471005.DWDB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDDW.DWD AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr$`DW(DDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW(....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr$`DW(DDHrD......Phase 3A@..DWDDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051448100514481005DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrCDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrCDW(DHrDWDHs~DWDHsPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051448100514481005.DWDB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrCDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrCDW(DHrDWDHs~DWDHsPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051448100514481005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrCDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrCDW(DHrDWDHs~DWDHsPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051448100514481005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWDYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrCDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrCDW(DHrDWDHs~DWDHsPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051449100514491005DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDDW.DWD AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr@DW(DHrۜBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW(....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr@DW(DHrۜ......Phase 3A@..DWDDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051449100514491005.DWDB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDDW.DWD AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr@DW(DHrۜBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW(....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr@DW(DHrۜ......Phase 3A@..DWDDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1005 10051450100514501005DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDшHr^DWDHsmxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDшHr^DW(DPHrPDWD<Hs{<DWDHsmxPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1005 10051450100514501005.DWDB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDшHr^DWDHsmxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDшHr^DW(DPHrPDWD<Hs{<DWDHsmxPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1005 10051450100514501005DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWD AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDшHr^DWDHsmxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDшHr^DW(DPHrPDWD<Hs{<DWDHsmxPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1005 10051450100514501005.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DWD.DWDWDYAYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDшHr^DWDHsmxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW(.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDшHr^DW(DPHrPDWD<Hs{<DWDHsmxPhase 3A@..DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1005 10051451100514511005DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWFDW.DWF AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD`Hrͪ`DW*DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW*....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD`Hrͪ`DW*DHr......Phase 3A@..DWFDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1005 10051451100514511005.DWFB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWFDW.DWF AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD`Hrͪ`DW*DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW*....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD`Hrͪ`DW*DHr......Phase 3A@..DWFDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061183100611831006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHr̐DWDHsv/DWDHs,Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061183100611831006.DW0BHVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHr̐DWDHsv/DWDHs,Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061183100611831006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHr̐DWDHsv/DWDHs,Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061183100611831006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs,Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHr̐DWDHsv/DWDHs,Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061184100611841006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDtHrDVDHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDtHrDVDHrx......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061184100611841006.DWB6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDtHrDVDHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDtHrDVDHrx......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061188100611881006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrsDWDHsHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrsDVDHr) DWDHssDWDHsHPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061188100611881006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrsDWDHsHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrsDVDHr) DWDHssDWDHsHPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061188100611881006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrsDWDHsHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrsDVDHr) DWDHssDWDHsHPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061188100611881006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrsDWDHsHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrsDVDHr) DWDHssDWDHsHPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061189100611891006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrsDVDHrTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrsDVDHrT......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061189100611891006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrsDVDHrTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrsDVDHrT......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061190100611901006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|HrM0DVDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|HrM0DVDHr8......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061190100611901006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|HrM0DVDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|HrM0DVDHr8......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061191100611911006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrmLDVDHr$BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrmLDVDHr$......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061191100611911006.DWB1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrmLDVDHr$BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrmLDVDHr$......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061196100611961006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD Hr͠DWDtHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD Hr͠DVDHrԼDWDHsuPDWDtHsSPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061196100611961006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD Hr͠DWDtHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD Hr͠DVDHrԼDWDHsuPDWDtHsSPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061196100611961006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD Hr͠DWDtHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD Hr͠DVDHrԼDWDHsuPDWDtHsSPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061196100611961006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD Hr͠DWDtHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD Hr͠DVDHrԼDWDHsuPDWDtHsSPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061200100612001006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDҴHrDWiDHs=pPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWSDWi.DWFPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDҴHrDWD4Hr`DWSDLHs DWiDHs=pPhase 3A@DW.DW$.12-15 YearsA YNN. DWEDWDWAYEARSDSAC4591001C4591001 1006 10061200100612001006.DW$B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDҴHrDWiDHs=pPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWSDWi.DWFPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDҴHrDWD4Hr`DWSDLHs DWiDHs=pPhase 3A@DW.DW$.12-15 YearsA YNN. DWEDWDWAYEARSDSA C4591001C4591001 1006 10061200100612001006DWSDWSBhREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDҴHrDWiDHs=pPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWSDWi.DWFPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDҴHrDWD4Hr`DWSDLHs DWiDHs=pPhase 3A@DW.DW$.12-15 YearsA YNN. DWEDWDWAYEARSDSA0C4591001C4591001 1006 10061200100612001006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDҴHrDWiDHs=pPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWSDWi.DWFPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDҴHrDWD4Hr`DWSDLHs DWiDHs=pPhase 3A@DW.DW$.12-15 YearsA YNN. DWEDWDWAYEARSDSA@C4591001C4591001 1006 10061200100612001006.DWCFOLLOW-UP BDISPOSITION EVENTLOST TO FOLLOW-UP APLost to follow-up, noncompliant DW$.DWDW$YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDҴHrDWiDHs=pPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWSDWi.DWFPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDҴHrDWD4Hr`DWSDLHs DWiDHs=pPhase 3A@DW.DW$.12-15 YearsA YNN. DWEDWDWAYEARSDSApC4591001C4591001 1006 10061201100612011006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDxHrxDWDpHr`BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDxHrxDWDpHr`......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061201100612011006.DW$B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDxHrxDWDpHr`BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDxHrxDWDpHr`......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061203100612031006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrXDVD8Hr׸BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrXDVD8Hr׸......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061203100612031006.DWB0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrXDVD8Hr׸BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrXDVD8Hr׸......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061206100612061006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW..DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDDHrDPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDPHrDWDDHrD......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061206100612061006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW..DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDDHrDPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDPHrDWDDHrD......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061206100612061006.DWBFOLLOW-UP BDISPOSITION EVENTWITHDRAWAL BY SUBJECT Bparent requested to withdraw consent DW..DWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDDHrDPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDPHrDWDDHrD......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSA`C4591001C4591001 1006 10061207100612071006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW..DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr DWDHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHr DWDHr......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061207100612071006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW..DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr DWDHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHr DWDHr......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061207100612071006.DWBFOLLOW-UP BDISPOSITION EVENTWITHDRAWAL BY SUBJECT Bparticipant withdrew consent DW..DWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr DWDHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHr DWDHr......Phase 3A@DW.DW.12-15 YearsA YNN. DWDWDWAYEARSDSA`C4591001C4591001 1006 10061209100612091006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr\DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr\DWDHr......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061209100612091006.DW"B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr\DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr\DWDHr......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061212100612121006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDʀHr>DWD<HsmPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDʀHr>DWDHrDWD(Hss(DWD<HsmPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061212100612121006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDʀHr>DWD<HsmPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDʀHr>DWDHrDWD(Hss(DWD<HsmPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061212100612121006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDʀHr>DWD<HsmPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDʀHr>DWDHrDWD(Hss(DWD<HsmPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061212100612121006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDʀHr>DWD<HsmPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDʀHr>DWDHrDWD(Hss(DWD<HsmPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061213100612131006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDDHr=DWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDDHr=DWDHr ......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061213100612131006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDDHr=DWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDDHr=DWDHr ......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061214100612141006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDߘHrSDWDՄHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDߘHrSDWDڬHrZDWDHssݤDWDՄHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061214100612141006.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDߘHrSDWDՄHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDߘHrSDWDڬHrZDWDHssݤDWDՄHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061214100612141006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDߘHrSDWDՄHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDߘHrSDWDڬHrZDWDHssݤDWDՄHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061214100612141006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSMABLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYPlacebo PLACEBO Placebo PLACEBO DVDߘHrSDWDՄHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDߘHrSDWDڬHrZDWDHssݤDWDՄHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061219100612191006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrtDWD$HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrtDWDHrSDWDHHsoHDWD$HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061219100612191006.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrtDWD$HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrtDWDHrSDWDHHsoHDWD$HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061219100612191006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrtDWD$HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrtDWDHrSDWDHHsoHDWD$HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061219100612191006.DWCOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW!YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrtDWD$HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrtDWDHrSDWDHHsoHDWD$HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061220100612201006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8Hr8DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW7BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8Hr8DWDHr......Phase 3A@..DW%DW12-15 YearsAYYNY. DW6DWDWAYEARSDSAC4591001C4591001 1006 10061220100612201006.DW%B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8Hr8DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW7BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8Hr8DWDHr......Phase 3A@..DW%DW12-15 YearsAYYNY. DW6DWDWAYEARSDSA C4591001C4591001 1006 10061221100612211006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr4......Phase 3A@DW.DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061221100612211006.DW%B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr4......Phase 3A@DW.DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061221100612211006.DWBFOLLOW-UP BDISPOSITION EVENTOTHER Apenrolled in C4591031 DW%DW.DW%YAYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr4......Phase 3A@DW.DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSAPC4591001C4591001 1006 10061223100612231006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr*DWDDHsGPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr*DWDHr|DWD{ Hsr$DWDDHsGPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061223100612231006.DW)B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr*DWDDHsGPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr*DWDHr|DWD{ Hsr$DWDDHsGPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061223100612231006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr*DWDDHsGPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr*DWDHr|DWD{ Hsr$DWDDHsGPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061223100612231006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr*DWDDHsGPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr*DWDHr|DWD{ Hsr$DWDDHsGPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061224100612241006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHr=HDWDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHr=HDWDHHr......Phase 3A@..DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061224100612241006.DW%B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHr=HDWDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHr=HDWDHHr......Phase 3A@..DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061226100612261006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrODWDHs@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrODWDHr \DWD$HsnT$DWDHs@Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061226100612261006.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrODWDHs@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrODWDHr \DWD$HsnT$DWDHs@Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061226100612261006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrODWDHs@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrODWDHr \DWD$HsnT$DWDHs@Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061226100612261006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW!YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrODWDHs@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrODWDHr \DWD$HsnT$DWDHs@Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061227100612271006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrPDWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrPDWDHr ......Phase 3A@..DW!DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061227100612271006.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrPDWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrPDWDHr ......Phase 3A@..DW!DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061228100612281006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrS@DWD4Hs/Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrS@DWDHHr/HDWD$HsnT$DWD4Hs/Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061228100612281006.DW$B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrS@DWD4Hs/Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrS@DWDHHr/HDWD$HsnT$DWD4Hs/Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061228100612281006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrS@DWD4Hs/Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrS@DWDHHr/HDWD$HsnT$DWD4Hs/Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061228100612281006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrS@DWD4Hs/Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrS@DWDHHr/HDWD$HsnT$DWD4Hs/Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061229100612291006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWjDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpPDWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpPDWD$Hr$DW9DHrhDWNDHs=Phase 3A@..DW(.12-15 YearsA YNN. DW5DWDWAYEARSDSAC4591001C4591001 1006 10061229100612291006.DW(B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWjDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpPDWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpPDWD$Hr$DW9DHrhDWNDHs=Phase 3A@..DW(.12-15 YearsA YNN. DW5DWDWAYEARSDSA C4591001C4591001 1006 10061229100612291006DW9DW9BIREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWjDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpPDWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpPDWD$Hr$DW9DHrhDWNDHs=Phase 3A@..DW(.12-15 YearsA YNN. DW5DWDWAYEARSDSA0C4591001C4591001 1006 10061229100612291006.DWjBzOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWjDW(YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpPDWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpPDWD$Hr$DW9DHrhDWNDHs=Phase 3A@..DW(.12-15 YearsA YNN. DW5DWDWAYEARSDSA@C4591001C4591001 1006 10061230100612301006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA MULTIPLE A`MULTIRACIAL A`YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWD0Hr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWD0Hr0......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061230100612301006.DW)B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA MULTIPLE A`MULTIRACIAL A`YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrpDWD0Hr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrpDWD0Hr0......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061231100612311006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrLDWDHr<BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrLDWDHr<......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061231100612311006.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrLDWDHr<BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrLDWDHr<......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061232100612321006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHrgDWD@Hss@DWDHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061232100612321006.DW#B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHrgDWD@Hss@DWDHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061232100612321006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHrgDWD@Hss@DWDHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061232100612321006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD0HrDWDHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD0HrDWDHrgDWD@Hss@DWDHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061233100612331006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrgDWD|Hss|DWDHsxPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061233100612331006.DW#B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrgDWD|Hss|DWDHsxPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061233100612331006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrgDWD|Hss|DWDHsxPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061233100612331006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrgDWD|Hss|DWDHsxPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061234100612341006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD~THrTDWD}(Hr7BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD~THrTDWD}(Hr7......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061234100612341006.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD~THrTDWD}(Hr7BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD~THrTDWD}(Hr7......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061235100612351006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD~HrDWD~Hs)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD~HrDWD}dHr7DWDɐHsuDWD~Hs)Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061235100612351006.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD~HrDWD~Hs)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD~HrDWD}dHr7DWDɐHsuDWD~Hs)Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061235100612351006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD~HrDWD~Hs)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD~HrDWD}dHr7DWDɐHsuDWD~Hs)Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061235100612351006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD~HrDWD~Hs)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD~HrDWD}dHr7DWDɐHsuDWD~Hs)Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061236100612361006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA ASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`Hr`DWDȠHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`Hr`DWDȠHr ......Phase 3A@..DW!DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061236100612361006.DW!B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA ASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`Hr`DWDȠHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`Hr`DWDȠHr ......Phase 3A@..DW!DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061237100612371006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrlDWD Hsn DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061237100612371006.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrlDWD Hsn DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061237100612371006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrlDWD Hsn DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061237100612371006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrlDWD Hsn DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061239100612391006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHre DWD`HsrDWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061239100612391006.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHre DWD`HsrDWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061239100612391006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHre DWD`HsrDWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061239100612391006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHre DWD`HsrDWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061241100612411006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061241100612411006.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061242100612421006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD~THrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD~THr......Phase 3A@..DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061242100612421006.DW%B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW%DW.DW% AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD~THrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD~THr......Phase 3A@..DW%DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061243100612431006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDDHrDWD~THrTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDDHrDWD~THrT......Phase 3A@..DW"DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061243100612431006.DW"B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDDHrDWD~THrTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDDHrDWD~THrT......Phase 3A@..DW"DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061244100612441006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD Hr ......Phase 3A@..DW"DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061244100612441006.DW"B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD Hr ......Phase 3A@..DW"DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061245100612451006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrDWD\Hr \DWDHssDWDhHshPhase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061245100612451006.DW"B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrDWD\Hr \DWDHssDWDhHshPhase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061245100612451006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrDWD\Hr \DWDHssDWDhHshPhase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061245100612451006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW"YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrDWDhHshPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrDWD\Hr \DWDHssDWDhHshPhase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061247100612471006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVE@Hr^DWDLHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVE@Hr^DWDHr`DWD`Hsn`DWDLHsSPhase 3A@....12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061247100612471006.DW$B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVE@Hr^DWDLHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVE@Hr^DWDHr`DWD`Hsn`DWDLHsSPhase 3A@....12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061247100612471006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVE@Hr^DWDLHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVE@Hr^DWDHr`DWD`Hsn`DWDLHsSPhase 3A@....12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061247100612471006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVE@Hr^DWDLHsSPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVE@Hr^DWDHr`DWD`Hsn`DWDLHsSPhase 3A@....12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061248100612481006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW%.DWDW% AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD$Hr/$DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD$Hr/$DWDHrMtDWDHstDWDHsPhase 3A@..DW%.12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061248100612481006.DW%B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW%.DWDW% AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD$Hr/$DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD$Hr/$DWDHrMtDWDHstDWDHsPhase 3A@..DW%.12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061248100612481006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW%.DWDW% AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD$Hr/$DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD$Hr/$DWDHrMtDWDHstDWDHsPhase 3A@..DW%.12-15 YearsAYYNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061248100612481006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW%.DWDW%YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD$Hr/$DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD$Hr/$DWDHrMtDWDHstDWDHsPhase 3A@..DW%.12-15 YearsAYYNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061249100612491006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWDHr......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061249100612491006.DW+B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWDHr......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061250100612501006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrIdDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrIdDWDHrDWDPHsv PDWDHs Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061250100612501006.DW+B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrIdDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrIdDWDHrDWDPHsv PDWDHs Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061250100612501006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrIdDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrIdDWDHrDWDPHsv PDWDHs Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061250100612501006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrIdDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrIdDWDHrDWDPHsv PDWDHs Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061252100612521006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr`DWDDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr`DWDDHrD......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061252100612521006.DW$B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr`DWDDHrDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr`DWDDHrD......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061253100612531006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrvdDWDHsCPPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrvdDWD Hr]DWD~Hsr'DWDHsCPPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061253100612531006.DW(B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrvdDWDHsCPPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrvdDWD Hr]DWD~Hsr'DWDHsCPPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061253100612531006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrvdDWDHsCPPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrvdDWD Hr]DWD~Hsr'DWDHsCPPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061253100612531006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDdHrvdDWDHsCPPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrvdDWD Hr]DWD~Hsr'DWDHsCPPhase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061254100612541006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrrDWDtHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrrDWDtHr......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061254100612541006.DW)B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrrDWDtHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrrDWDtHr......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061256100612561006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD\HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD\Hr......Phase 3A@..DW(DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061256100612561006.DW(B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWD\HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWD\Hr......Phase 3A@..DW(DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061257100612571006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWkDW$ AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWODŔHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW:DWO.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHr|DW:D\Hr\DWODŔHslPhase 3A@..DW$.12-15 YearsA YNN. DW5DWDWAYEARSDSAC4591001C4591001 1006 10061257100612571006.DW$B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWkDW$ AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWODŔHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW:DWO.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHr|DW:D\Hr\DWODŔHslPhase 3A@..DW$.12-15 YearsA YNN. DW5DWDWAYEARSDSA C4591001C4591001 1006 10061257100612571006DW:DW:BGREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWkDW$ AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWODŔHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW:DWO.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHr|DW:D\Hr\DWODŔHslPhase 3A@..DW$.12-15 YearsA YNN. DW5DWDWAYEARSDSA0C4591001C4591001 1006 10061257100612571006.DWkBxOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWkDW$YAYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWODŔHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW:DWO.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHr|DW:D\Hr\DWODŔHslPhase 3A@..DW$.12-15 YearsA YNN. DW5DWDWAYEARSDSA@C4591001C4591001 1006 10061258100612581006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSMANATIVE HAWAIIAN OR OTHER PACIFIC ISLANDERAPNATIVE HAWAIIAN OR OTHER PACIFIC ISLANDERAPYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr$DW D}Hr!\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr$DW D}Hr!\......Phase 3A@..DW/DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061258100612581006.DW/B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSMANATIVE HAWAIIAN OR OTHER PACIFIC ISLANDERAPNATIVE HAWAIIAN OR OTHER PACIFIC ISLANDERAPYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr$DW D}Hr!\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr$DW D}Hr!\......Phase 3A@..DW/DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061259100612591006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHr8DWoDlHsEZPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWVDWo.DW@Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHr8DW DHr3,DWVDHs$hDWoDlHsEZPhase 3A@..DW).12-15 YearsA YNN. DW?DWDWAYEARSDSAC4591001C4591001 1006 10061259100612591006.DW)B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHr8DWoDlHsEZPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWVDWo.DW@Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHr8DW DHr3,DWVDHs$hDWoDlHsEZPhase 3A@..DW).12-15 YearsA YNN. DW?DWDWAYEARSDSA C4591001C4591001 1006 10061259100612591006DWVDWVB`REPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHr8DWoDlHsEZPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWVDWo.DW@Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHr8DW DHr3,DWVDHs$hDWoDlHsEZPhase 3A@..DW).12-15 YearsA YNN. DW?DWDWAYEARSDSA0C4591001C4591001 1006 10061259100612591006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHr8DWoDlHsEZPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWVDWo.DW@Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHr8DW DHr3,DWVDHs$hDWoDlHsEZPhase 3A@..DW).12-15 YearsA YNN. DW?DWDWAYEARSDSA@C4591001C4591001 1006 10061260100612601006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr9pDWD8Hs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr9pDW DHr3hDWDHsr14DWD8Hs8Phase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061260100612601006.DW)B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr9pDWD8Hs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr9pDW DHr3hDWDHsr14DWD8Hs8Phase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061260100612601006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr9pDWD8Hs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr9pDW DHr3hDWDHsr14DWD8Hs8Phase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061260100612601006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr9pDWD8Hs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr9pDW DHr3hDWDHsr14DWD8Hs8Phase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061261100612611006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD HrDW D$Hr3BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD HrDW D$Hr3......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061261100612611006.DW)B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD HrDW D$Hr3BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD HrDW D$Hr3......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061262100612621006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWD\Hsz\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWD<Hr<DWDHs}.hDWD\Hsz\Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061262100612621006.DW0B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWD\Hsz\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWD<Hr<DWDHs}.hDWD\Hsz\Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061262100612621006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWD\Hsz\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWD<Hr<DWDHs}.hDWD\Hsz\Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061262100612621006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrDWD\Hsz\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrDWD<Hr<DWDHs}.hDWD\Hsz\Phase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061263100612631006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,DW.DW, AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW D\Hr@\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW D\Hr@\......Phase 3A@..DW,DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061263100612631006.DW,B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,DW.DW, AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW D\Hr@\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW D\Hr@\......Phase 3A@..DW,DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061264100612641006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD HrDW DHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD HrDW DHrH......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061264100612641006.DW*B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD HrDW DHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD HrDW DHrH......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061265100612651006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+..DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHru DWD{ Hrp BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHru DWD{ Hrp ......Phase 3A@DW.DW+.12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061265100612651006.DW+B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+..DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHru DWD{ Hrp BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHru DWD{ Hrp ......Phase 3A@DW.DW+.12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061265100612651006.DWBFOLLOW-UP BDISPOSITION EVENTNO LONGER MEETS ELIGIBILITY CRITERIABRECEIVED COVID VACCINE OUTSIDE STUDY DW+..DW+YAYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHru DWD{ Hrp BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHru DWD{ Hrp ......Phase 3A@DW.DW+.12-15 YearsAYYNN. DWDWDWAYEARSDSAPC4591001C4591001 1006 10061266100612661006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWpDW1 AYEARSFA MULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD4Hr4DWTDtHs!tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW?DWT.DW>Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4Hr4DWDdHrŐdDW?DHs-hDWTDtHs!tPhase 3A@..DW1.12-15 YearsA YNN. DW=DWDWAYEARSDSAC4591001C4591001 1006 10061266100612661006.DW1B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWpDW1 AYEARSFA MULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD4Hr4DWTDtHs!tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW?DWT.DW>Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4Hr4DWDdHrŐdDW?DHs-hDWTDtHs!tPhase 3A@..DW1.12-15 YearsA YNN. DW=DWDWAYEARSDSA C4591001C4591001 1006 10061266100612661006DW?DW?BHREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWpDW1 AYEARSFA MULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD4Hr4DWTDtHs!tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW?DWT.DW>Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4Hr4DWDdHrŐdDW?DHs-hDWTDtHs!tPhase 3A@..DW1.12-15 YearsA YNN. DW=DWDWAYEARSDSA0C4591001C4591001 1006 10061266100612661006.DWpByOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWpDW1YAYEARSFA MULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD4Hr4DWTDtHs!tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW?DWT.DW>Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4Hr4DWDdHrŐdDW?DHs-hDWTDtHs!tPhase 3A@..DW1.12-15 YearsA YNN. DW=DWDWAYEARSDSA@C4591001C4591001 1006 10061267100612671006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW:..DW: AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDݸHs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrڜDWDpHsSpDWDݸHs8Phase 3A@..DW:.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061267100612671006.DW:BCVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW:..DW: AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDݸHs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrڜDWDpHsSpDWDݸHs8Phase 3A@..DW:.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061267100612671006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW:..DW: AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDݸHs8Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDHrڜDWDpHsSpDWDݸHs8Phase 3A@..DW:.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061269100612691006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061269100612691006.DW1B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061270100612701006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWkDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr@DWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr@DWDTHrłTDW9DXHr.DWNDHs=Phase 3A@..DW*.12-15 YearsA YNN. DW5DWDWAYEARSDSAC4591001C4591001 1006 10061270100612701006.DW*B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWkDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr@DWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr@DWDTHrłTDW9DXHr.DWNDHs=Phase 3A@..DW*.12-15 YearsA YNN. DW5DWDWAYEARSDSA C4591001C4591001 1006 10061270100612701006DW9DW9BAREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWkDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr@DWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr@DWDTHrłTDW9DXHr.DWNDHs=Phase 3A@..DW*.12-15 YearsA YNN. DW5DWDWAYEARSDSA0C4591001C4591001 1006 10061270100612701006.DWkBsOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWkDW*YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr@DWNDHs=Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW9DWN.DW6Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr@DWDTHrłTDW9DXHr.DWNDHs=Phase 3A@..DW*.12-15 YearsA YNN. DW5DWDWAYEARSDSA@C4591001C4591001 1006 10061271100612711006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr4DW DHrnxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr4DW DHrnx......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061271100612711006.DW*B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr4DW DHrnxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr4DW DHrnx......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061272100612721006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA BLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDdHrDWDHsrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DV.DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDdHrDWDHsr......Phase 3A@..DW/DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061272100612721006.DWBVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA BLACK OR AFRICAN AMERICAN A BLACK OR AFRICAN AMERICAN A YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDdHrDWDHsrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DV.DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDdHrDWDHsr......Phase 3A@..DW/DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061273100612731006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,Hr'DWDLHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,Hr'DWDHrjDWDְHssѰDWDLHs<Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061273100612731006.DW,B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,Hr'DWDLHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,Hr'DWDHrjDWDְHssѰDWDLHs<Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061273100612731006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,Hr'DWDLHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,Hr'DWDHrjDWDְHssѰDWDLHs<Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061273100612731006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW,YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,Hr'DWDLHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,Hr'DWDHrjDWDְHssѰDWDLHs<Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061274100612741006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,DW.DW, AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDPHr?DWDHr1BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDPHr?DWDHr1......Phase 3A@..DW,DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061274100612741006.DW,B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,DW.DW, AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDPHr?DWDHr1BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDPHr?DWDHr1......Phase 3A@..DW,DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061276100612761006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrKDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrKDWDHrִDWDHst8DWDHs(Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061276100612761006.DW,B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrKDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrKDWDHrִDWDHst8DWDHs(Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061276100612761006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrKDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrKDWDHrִDWDHst8DWDHs(Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061276100612761006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW,YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrKDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrKDWDHrִDWDHst8DWDHs(Phase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061277100612771006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpDWD Hs8 Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpDWDHrpDWDHssDWD Hs8 Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061277100612771006.DW/B6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpDWD Hs8 Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpDWDHrpDWDHssDWD Hs8 Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061277100612771006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpDWD Hs8 Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpDWDHrpDWDHssDWD Hs8 Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061277100612771006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrpDWD Hs8 Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrpDWDHrpDWDHssDWD Hs8 Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061278100612781006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW DHrOBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW DHrO......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061278100612781006.DW)B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW DHrOBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW DHrO......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061279100612791006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDHsJPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDW DtHrėDWDHHsrBDWDHsJPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061279100612791006.DW)B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDHsJPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDW DtHrėDWDHHsrBDWDHsJPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061279100612791006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDHsJPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDW DtHrėDWDHHsrBDWDHsJPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061279100612791006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDHsJPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDW DtHrėDWDHHsrBDWDHsJPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061280100612801006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr6DBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr6D......Phase 3A@DW.DW1DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061280100612801006.DW1B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr6DBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr6D......Phase 3A@DW.DW1DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061280100612801006.DWBFOLLOW-UP BDISPOSITION EVENTOTHER Apenrolled in C4591031 DW1DW.DW1YAYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr6DBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr6D......Phase 3A@DW.DW1DW12-15 YearsAYYNY. DWDWDWAYEARSDSAPC4591001C4591001 1006 10061282100612821006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW3DW.DW3 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD\HrDWDtHr2tBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD\HrDWDtHr2t......Phase 3A@..DW3DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061282100612821006.DW3B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW3DW.DW3 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD\HrDWDtHr2tBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD\HrDWDtHr2t......Phase 3A@..DW3DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061283100612831006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDŔHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrDWDؐHrpDWDxHsvxDWDŔHsPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061283100612831006.DW,B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDŔHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrDWDؐHrpDWDxHsvxDWDŔHsPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061283100612831006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDŔHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrDWDؐHrpDWDxHsvxDWDŔHsPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061283100612831006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW,YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrDWDŔHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrDWDؐHrpDWDxHsvxDWDŔHsPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061284100612841006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hrȅ0DWD$Hs|DWDLHsLPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061284100612841006.DW,B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hrȅ0DWD$Hs|DWDLHsLPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061284100612841006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW, AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hrȅ0DWD$Hs|DWDLHsLPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061284100612841006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW,.DWDW,YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDLHsLPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hrȅ0DWD$Hs|DWDLHsLPhase 3A@..DW,.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061285100612851006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW7.DWDW7 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDôHs4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrpDWDpHspDWDôHs4Phase 3A@..DW7.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061285100612851006.DW7B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW7.DWDW7 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDôHs4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrpDWDpHspDWDôHs4Phase 3A@..DW7.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061285100612851006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW7.DWDW7 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDôHs4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrpDWDpHspDWDôHs4Phase 3A@..DW7.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061285100612851006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW7.DWDW7YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDôHs4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrpDWDpHspDWDôHs4Phase 3A@..DW7.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061286100612861006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrytBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHryt......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061286100612861006.DW0B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0DW.DW0 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrytBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHryt......Phase 3A@..DW0DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061287100612871006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/..DW/ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHr̄xPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDWDHr̄x......Phase 3A@DW.DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061287100612871006.DW/B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/..DW/ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHr̄xPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDWDHr̄x......Phase 3A@DW.DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061287100612871006.DWBFOLLOW-UP BDISPOSITION EVENTWITHDRAWAL BY SUBJECT BDiscontinued DW/..DW/YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHr̄xPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDWDHr̄x......Phase 3A@DW.DW/.12-15 YearsA YNN. DWDWDWAYEARSDSApC4591001C4591001 1006 10061288100612881006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr̄<BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW@BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr̄<......Phase 3A@DW.DW/DW12-15 YearsA YNY. DW?DWDWAYEARSDSAC4591001C4591001 1006 10061288100612881006.DW/B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr̄<BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW@BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr̄<......Phase 3A@DW.DW/DW12-15 YearsA YNY. DW?DWDWAYEARSDSA C4591001C4591001 1006 10061288100612881006.DWBFOLLOW-UP BDISPOSITION EVENTOTHER Apenrolled in C4591031 DW/DW.DW/YAYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr̄<BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW@BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr̄<......Phase 3A@DW.DW/DW12-15 YearsA YNY. DW?DWDWAYEARSDSA@C4591001C4591001 1006 10061289100612891006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWD|HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWD|Hr......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061289100612891006.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrHDWD|HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrHDWD|Hr......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061290100612901006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr8......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061290100612901006.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6DW.DW6 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr8......Phase 3A@..DW6DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061291100612911006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD@HrDWDHs~XPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD@HrDWDHrtDWDHs{ذDWDHs~XPhase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061291100612911006.DW6B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD@HrDWDHs~XPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD@HrDWDHrtDWDHs{ذDWDHs~XPhase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061291100612911006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD@HrDWDHs~XPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD@HrDWDHrtDWDHs{ذDWDHs~XPhase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061291100612911006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW6.DWDW6YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD@HrDWDHs~XPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD@HrDWDHrtDWDHs{ذDWDHs~XPhase 3A@..DW6.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061292100612921006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<HrDWDHsAxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD<HrDWDHr`DWD|Hsn8|DWDHsAxPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061292100612921006.DW1B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<HrDWDHsAxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD<HrDWDHr`DWD|Hsn8|DWDHsAxPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061292100612921006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<HrDWDHsAxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD<HrDWDHr`DWD|Hsn8|DWDHsAxPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061292100612921006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<HrDWDHsAxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD<HrDWDHr`DWD|Hsn8|DWDHsAxPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061293100612931006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr`BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr`......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061293100612931006.DW1B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1DW.DW1 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr`BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr`......Phase 3A@..DW1DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061294100612941006DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDԔHrͲDWDHsvgDWDHsPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061294100612941006.DW0B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDԔHrͲDWDHsvgDWDHsPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061294100612941006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDԔHrͲDWDHsvgDWDHsPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061294100612941006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW0.DWDW0YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDԔHrͲDWDHsvgDWDHsPhase 3A@..DW0.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061295100612951006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrc DWD4HsAPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrc DWDHraDWDHsn8DWD4HsAPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061295100612951006.DW1B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrc DWD4HsAPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrc DWDHraDWDHsn8DWD4HsAPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061295100612951006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrc DWD4HsAPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrc DWDHraDWDHsn8DWD4HsAPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061295100612951006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW1.DWDW1YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrc DWD4HsAPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrc DWDHraDWDHsn8DWD4HsAPhase 3A@..DW1.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061296100612961006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW7..DW7 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD8Hr8DWDHrpPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWD8Hr8DWDHrp......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061296100612961006.DW7B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW7..DW7 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD8Hr8DWDHrpPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWD8Hr8DWDHrp......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061296100612961006.DWBFOLLOW-UP BDISPOSITION EVENTLOST TO FOLLOW-UP APunable to contact DW7..DW7YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD8Hr8DWDHrpPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWD8Hr8DWDHrp......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSAPC4591001C4591001 1006 10061297100612971006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW7..DW7 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDtHrtDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDtHrtDWDHr4......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061297100612971006.DW7B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW7..DW7 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDtHrtDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDtHrtDWDHr4......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061297100612971006.DWBFOLLOW-UP BDISPOSITION EVENTLOST TO FOLLOW-UP APunable to contact DW7..DW7YAYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDtHrtDWDHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDtHrtDWDHr4......Phase 3A@DW.DW7.12-15 YearsA YNN. DWDWDWAYEARSDSAPC4591001C4591001 1006 10061298100612981006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr9DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr9DWDHr DWD@HstDWDHsPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1006 10061298100612981006.DW8B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr9DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr9DWDHr DWD@HstDWDHsPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1006 10061298100612981006DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr9DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr9DWDHr DWD@HstDWDHsPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1006 10061298100612981006.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr9DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr9DWDHr DWD@HstDWDHsPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1006 10061299100612991006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDLHrLDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDLHrLDWDHr......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061299100612991006.DW?B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDLHrLDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDLHrLDWDHr......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1006 10061300100613001006DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWADW.DWA AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr1DW$DHr޼BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW$....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr1DW$DHr޼......Phase 3A@..DWADW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1006 10061300100613001006.DWAB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWADW.DWA AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr1DW$DHr޼BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW$....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr1DW$DHr޼......Phase 3A@..DWADW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071409100714091007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|Hrad|DWDHsnBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DV.DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|Hrad|DWDHsn......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071409100714091007.DWBVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|Hrad|DWDHsnBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DV.DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|Hrad|DWDHsn......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071414100714141007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraoDWDHsaHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHraoDVDHr}+0DWDHsu|DWDHsaHPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071414100714141007.DVB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraoDWDHsaHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHraoDVDHr}+0DWDHsu|DWDHsaHPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071414100714141007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDV AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraoDWDHsaHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHraoDVDHr}+0DWDHsu|DWDHsaHPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071414100714141007.DWCOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DVDWDWDVYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraoDWDHsaHPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHraoDVDHr}+0DWDHsu|DWDHsaHPhase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071415100714151007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrayDVDHrPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHrayDVDHr......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071415100714151007.DWBNVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrayDVDHrPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHrayDVDHr......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071417100714171007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDPHraPDVDHr}#tBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DW@BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDPHraPDVDHr}#t......Phase 3A@..DVDW12-15 YearsAYYNY. DW?DWDWAYEARSDSAC4591001C4591001 1007 10071417100714171007.DVB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDPHraPDVDHr}#tBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DW@BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDPHraPDVDHr}#t......Phase 3A@..DVDW12-15 YearsAYYNY. DW?DWDWAYEARSDSA C4591001C4591001 1007 10071428100714281007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHraDVDHr}YPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHraDVDHr}Y......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071428100714281007.DVB6VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHraDVDHr}YPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHraDVDHr}Y......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071429100714291007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraDVD`Hr}\Placebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHraDVD`Hr}\......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071429100714291007.DVB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DVDW.DV AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHraDVD`Hr}\Placebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHraDVD`Hr}\......Phase 3A@..DVDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071467100714671007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr8DVDdHridBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWSBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr8DVDdHrid......Phase 3A@..DWDW12-15 YearsAYYNY. DWRDWDWAYEARSDSAC4591001C4591001 1007 10071467100714671007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr8DVDdHridBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWSBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr8DVDdHrid......Phase 3A@..DWDW12-15 YearsAYYNY. DWRDWDWAYEARSDSA C4591001C4591001 1007 10071469100714691007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrXDVDHr|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrXDVDHr|......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071469100714691007.DWB4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrXDVDHr|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrXDVDHr|......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071471100714711007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDVD0Hr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDVD0Hr0......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071471100714711007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDVD0Hr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDVD0Hr0......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071472100714721007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDhHs,hPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDVDHrjDWDHsr_`DWDhHs,hPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071472100714721007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDhHs,hPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDVDHrjDWDHsr_`DWDhHs,hPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071472100714721007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDhHs,hPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDVDHrjDWDHsr_`DWDhHs,hPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071472100714721007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDhHs,hPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDVDHrjDWDHsr_`DWDhHs,hPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071475100714751007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHrDVDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHrDVDHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071475100714751007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHrDVDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHrDVDHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071476100714761007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHr DVDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHr DVDHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071476100714761007.DWB4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHr DVDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHr DVDHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071478100714781007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHHrHDWDLHsv`LDWDHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071478100714781007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHHrHDWDLHsv`LDWDHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071478100714781007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHHrHDWDLHsv`LDWDHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071478100714781007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHHrHDWDLHsv`LDWDHsPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071480100714801007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr!|DWD$HsIPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr!|DVDHrDWDxHsrlDWD$HsIPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071480100714801007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr!|DWD$HsIPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr!|DVDHrDWDxHsrlDWD$HsIPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071480100714801007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr!|DWD$HsIPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr!|DVDHrDWDxHsrlDWD$HsIPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071480100714801007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr!|DWD$HsIPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr!|DVDHrDWDxHsrlDWD$HsIPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071481100714811007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDXHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHr DWDHsDWDXHsPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071481100714811007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDXHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHr DWDHsDWDXHsPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071481100714811007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDXHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHr DWDHsDWDXHsPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071481100714811007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDXHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDVDHr DWDHsDWDXHsPhase 3A@..DW.12-15 YearsAYYNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071482100714821007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr DVD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr DVD Hr ......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071482100714821007.DWB4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr DVD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr DVD Hr ......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071483100714831007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWvD$HsN$Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWaDWv.DWKPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DVD4Hr۴DWaDHs3ILDWvD$HsN$Phase 3A@..DW".12-15 YearsA YNN. DWJDWDWAYEARSDSAC4591001C4591001 1007 10071483100714831007.DW"B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWvD$HsN$Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWaDWv.DWKPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DVD4Hr۴DWaDHs3ILDWvD$HsN$Phase 3A@..DW".12-15 YearsA YNN. DWJDWDWAYEARSDSA C4591001C4591001 1007 10071483100714831007DWaDWaBxREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWvD$HsN$Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWaDWv.DWKPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DVD4Hr۴DWaDHs3ILDWvD$HsN$Phase 3A@..DW".12-15 YearsA YNN. DWJDWDWAYEARSDSA0C4591001C4591001 1007 10071483100714831007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW"YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWvD$HsN$Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWaDWv.DWKPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DVD4Hr۴DWaDHs3ILDWvD$HsN$Phase 3A@..DW".12-15 YearsA YNN. DWJDWDWAYEARSDSA@C4591001C4591001 1007 10071484100714841007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrpDWD Hs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrpDVDHrhDWDHsulDWD Hs Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071484100714841007.DW"B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrpDWD Hs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrpDVDHrhDWDHsulDWD Hs Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071484100714841007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrpDWD Hs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrpDVDHrhDWDHsulDWD Hs Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071484100714841007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW"YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDpHrpDWD Hs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDpHrpDVDHrhDWDHsulDWD Hs Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071485100714851007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDDVD,Hr,BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDDVD,Hr,......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071485100714851007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDDVD,Hr,BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDDVD,Hr,......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071488100714881007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr_DVDHr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr_DVDHr@......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071488100714881007.DWB3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr_DVDHr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr_DVDHr@......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071490100714901007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrlDVDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrlDVDHHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071490100714901007.DWB4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrlDVDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrlDVDHHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071492100714921007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD8Hrs8DVD|Hr|Placebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVD8Hrs8DVD|Hr|......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071492100714921007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD8Hrs8DVD|Hr|Placebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVD8Hrs8DVD|Hr|......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071494100714941007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|HrqDVD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|HrqDVD Hr ......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071494100714941007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD|HrqDVD Hr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD|HrqDVD Hr ......Phase 3A@..DWDW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071495100714951007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr|DWDtHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr|DVD HrDWDݸHs}8DWDtHs<Phase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071495100714951007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr|DWDtHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr|DVD HrDWDݸHs}8DWDtHs<Phase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071495100714951007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr|DWDtHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr|DVD HrDWDݸHs}8DWDtHs<Phase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071495100714951007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr|DWDtHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr|DVD HrDWDݸHs}8DWDtHs<Phase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071496100714961007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHr`DWDHsQXPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr`DVDHr0DWDHs{DWDHsQXPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071496100714961007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHr`DWDHsQXPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr`DVDHr0DWDHs{DWDHsQXPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071496100714961007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDW AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHr`DWDHsQXPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr`DVDHr0DWDHs{DWDHsQXPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071496100714961007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW.DWDWYAYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDHr`DWDHsQXPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDV.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr`DVDHr0DWDHs{DWDHsQXPhase 3A@..DW.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071497100714971007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrĸDVDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrĸDVDHHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071497100714971007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrĸDVDHHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrĸDVDHHr......Phase 3A@..DWDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071499100714991007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDVD(HrPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDVD(Hr......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071499100714991007.DWB1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDVD(HrPlacebo Placebo 12-15 YearsA . . .DVDV....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDVD(Hr......Phase 3A@..DWDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071500100715001007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDVDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDVDHr8......Phase 3A@..DWDW12-15 YearsA YNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071500100715001007.DWB2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWDW.DW AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDVDHr8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDV....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDVDHr8......Phase 3A@..DWDW12-15 YearsA YNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071504100715041007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,Hr,DWDHrOTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,Hr,DWDHrOT......Phase 3A@..DW#DW12-15 YearsAYYNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071504100715041007.DW#B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,Hr,DWDHrOTBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,Hr,DWDHrOT......Phase 3A@..DW#DW12-15 YearsAYYNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071505100715051007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWDˆHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DWDHr,DWDHs_<DWDˆHs3Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071505100715051007.DW(B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWDˆHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DWDHr,DWDHs_<DWDˆHs3Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071505100715051007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWDˆHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DWDHr,DWDHs_<DWDˆHs3Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071505100715051007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWDˆHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DWDHr,DWDHs_<DWDˆHs3Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071506100715061007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDxHrxDWD,HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW}BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDxHrxDWD,Hr......Phase 3A@..DW!DW12-15 YearsAYYNY. DW|DWDWAYEARSDSAC4591001C4591001 1007 10071506100715061007.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDxHrxDWD,HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW}BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDxHrxDWD,Hr......Phase 3A@..DW!DW12-15 YearsAYYNY. DW|DWDWAYEARSDSA C4591001C4591001 1007 10071507100715071007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDdHrdDWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrdDWDHr`DWDHsu (DWD8HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071507100715071007.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDdHrdDWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrdDWDHr`DWDHsu (DWD8HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071507100715071007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDdHrdDWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrdDWDHr`DWDHsu (DWD8HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071507100715071007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW!YAYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DVDdHrdDWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDdHrdDWDHr`DWDHsu (DWD8HsPhase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071508100715081007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr)DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr)DWDHr......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071508100715081007.DW$B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr)DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr)DWDHr......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071509100715091007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDθHr6DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDθHr6DWDHrOTDWDHsv&DWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071509100715091007.DW#B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDθHr6DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDθHr6DWDHrOTDWDHsv&DWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071509100715091007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDθHr6DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDθHr6DWDHrOTDWDHsv&DWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071509100715091007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDθHr6DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDθHr6DWDHrOTDWDHsv&DWDHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071511100715111007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrTDWDHs7\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrTDWDHrDWD Hss DWDHs7\Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071511100715111007.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrTDWDHs7\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrTDWDHrDWD Hss DWDHs7\Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071511100715111007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW! AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrTDWDHs7\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrTDWDHrDWD Hss DWDHs7\Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071511100715111007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW!.DWDW!YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrTDWDHs7\Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrTDWDHrDWD Hss DWDHs7\Phase 3A@..DW!.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071512100715121007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrZXDWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrZXDWDHrH......Phase 3A@..DW!DW12-15 YearsAYYNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071512100715121007.DW!B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW!DW.DW! AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrZXDWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrZXDWDHrH......Phase 3A@..DW!DW12-15 YearsAYYNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071514100715141007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrYDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrYDWDHr......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071514100715141007.DW$B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrYDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrYDWDHr......Phase 3A@..DW$DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071515100715151007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrCDWDHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHHrCDWDHr......Phase 3A@..DW"DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071515100715151007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHrCDWDHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHHrCDWDHr......Phase 3A@..DW"DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071516100715161007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrB$DWDLHs?Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrB$DWDPHr PDWDԔHssϔDWDLHs?Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071516100715161007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrB$DWDLHs?Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrB$DWDPHr PDWDԔHssϔDWDLHs?Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071516100715161007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrB$DWDLHs?Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrB$DWDPHr PDWDԔHssϔDWDLHs?Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071516100715161007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW"YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrB$DWDLHs?Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrB$DWDPHr PDWDԔHssϔDWDLHs?Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071517100715171007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,HrPDWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,HrPDWDHrH......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071517100715171007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,HrPDWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,HrPDWDHrH......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071518100715181007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`HrXDWDxHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`HrXDWDxHrx......Phase 3A@..DW"DW12-15 YearsA YNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071518100715181007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`HrXDWDxHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`HrXDWDxHrx......Phase 3A@..DW"DW12-15 YearsA YNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071519100715191007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHraDWwDtHsP)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWbDWw.DWaPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHraDWDHr DWbDHHs4LHDWwDtHsP)Phase 3A@..DW#.12-15 YearsA YNN. DW`DWDWAYEARSDSAC4591001C4591001 1007 10071519100715191007.DW#B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHraDWwDtHsP)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWbDWw.DWaPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHraDWDHr DWbDHHs4LHDWwDtHsP)Phase 3A@..DW#.12-15 YearsA YNN. DW`DWDWAYEARSDSA C4591001C4591001 1007 10071519100715191007DWbDWbBrREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHraDWwDtHsP)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWbDWw.DWaPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHraDWDHr DWbDHHs4LHDWwDtHsP)Phase 3A@..DW#.12-15 YearsA YNN. DW`DWDWAYEARSDSA0C4591001C4591001 1007 10071519100715191007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHHraDWwDtHsP)Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWbDWw.DWaPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHHraDWDHr DWbDHHs4LHDWwDtHsP)Phase 3A@..DW#.12-15 YearsA YNN. DW`DWDWAYEARSDSA@C4591001C4591001 1007 10071520100715201007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrbDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrbDWD|Hr |DWD@Hs@DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071520100715201007.DW#B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrbDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrbDWD|Hr |DWD@Hs@DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071520100715201007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrbDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrbDWD|Hr |DWD@Hs@DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071520100715201007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrbDWD(Hs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrbDWD|Hr |DWD@Hs@DWD(Hs(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071521100715211007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDˆHr|DWDLHr:LBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDˆHr|DWDLHr:L......Phase 3A@..DW$DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071521100715211007.DW$B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDˆHr|DWDLHr:LBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDˆHr|DWDLHr:L......Phase 3A@..DW$DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071522100715221007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrXDWDHs `Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrXDWD|Hr7|DWD0Hs~)0DWDHs `Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071522100715221007.DW$B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrXDWDHs `Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrXDWD|Hr7|DWD0Hs~)0DWDHs `Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071522100715221007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrXDWDHs `Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrXDWD|Hr7|DWD0Hs~)0DWDHs `Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071522100715221007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrXDWDHs `Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrXDWD|Hr7|DWD0Hs~)0DWDHs `Phase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071523100715231007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrxDWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrxDWDHr ......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071523100715231007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrxDWDHr BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrxDWDHr ......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071524100715241007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWvDW* AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrdDWUDHs#rPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW@DWU.DW1Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrdDWDHr DW@DLHsLDWUDHs#rPhase 3A@..DW*.12-15 YearsA YNN. DW0DWDWAYEARSDSAC4591001C4591001 1007 10071524100715241007.DW*B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWvDW* AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrdDWUDHs#rPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW@DWU.DW1Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrdDWDHr DW@DLHsLDWUDHs#rPhase 3A@..DW*.12-15 YearsA YNN. DW0DWDWAYEARSDSA C4591001C4591001 1007 10071524100715241007DW@DW@BPREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWvDW* AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrdDWUDHs#rPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW@DWU.DW1Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrdDWDHr DW@DLHsLDWUDHs#rPhase 3A@..DW*.12-15 YearsA YNN. DW0DWDWAYEARSDSA0C4591001C4591001 1007 10071524100715241007.DWvBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWvDW*YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrdDWUDHs#rPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW@DWU.DW1Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrdDWDHr DW@DLHsLDWUDHs#rPhase 3A@..DW*.12-15 YearsA YNN. DW0DWDWAYEARSDSA@C4591001C4591001 1007 10071525100715251007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD@HrDWD@Hr @BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD@HrDWD@Hr @......Phase 3A@..DW*DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071525100715251007.DW*B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD@HrDWD@Hr @BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD@HrDWD@Hr @......Phase 3A@..DW*DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071526100715261007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHrDWDhHr-hBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHrDWDhHr-h......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071526100715261007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHHrDWDhHr-hBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHHrDWDhHr-h......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071527100715271007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDǰHs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDWDXHr.XDWDHsDWDǰHs0Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071527100715271007.DW"B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDǰHs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDWDXHr.XDWDHsDWDǰHs0Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071527100715271007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW" AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDǰHs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDWDXHr.XDWDHsDWDǰHs0Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071527100715271007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW".DWDW"YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD,HrDWDǰHs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD,HrDWDXHr.XDWDHsDWDǰHs0Phase 3A@..DW".12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071528100715281007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD@HryPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDWD@Hry......Phase 3A@..DW#DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071528100715281007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD@HryPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrDWD@Hry......Phase 3A@..DW#DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071529100715291007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA MULTIPLE A`MULTIRACIAL A`YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD0Hr0DWDHrLHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD0Hr0DWDHrLH......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071529100715291007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA MULTIPLE A`MULTIRACIAL A`YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD0Hr0DWDHrLHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD0Hr0DWDHrLH......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071530100715301007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHrP......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071530100715301007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHrP......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071531100715311007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDhHrhDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDhHrhDWDHrSDWDdHs|DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071531100715311007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDhHrhDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDhHrhDWDHrSDWDdHs|DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071531100715311007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDhHrhDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDhHrhDWDHrSDWDdHs|DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071531100715311007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDhHrhDWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDhHrhDWDHrSDWDdHs|DWD\HsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071533100715331007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHrxDWDdHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHrxDWDHrbPDWDHs~$DWDdHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071533100715331007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHrxDWDdHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHrxDWDHrbPDWDHs~$DWDdHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071533100715331007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHrxDWDdHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHrxDWDHrbPDWDHs~$DWDdHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071533100715331007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDxHrxDWDdHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDxHrxDWDHrbPDWDHs~$DWDdHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071535100715351007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr DWD<HrnBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr DWD<Hrn......Phase 3A@..DW#DW12-15 YearsA YNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071535100715351007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD Hr DWD<HrnBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD Hr DWD<Hrn......Phase 3A@..DW#DW12-15 YearsA YNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071536100715361007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDߘHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDߘHrH......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071536100715361007.DW"B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDߘHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDߘHrH......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071537100715371007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDǰHrҰDWDHr\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDǰHrҰDWDHr\......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071537100715371007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDǰHrҰDWDHr\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDǰHrҰDWDHr\......Phase 3A@..DW#DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071539100715391007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDˬHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDWDʀHrDWD4HsDWDˬHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071539100715391007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDˬHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDWDʀHrDWD4HsDWDˬHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071539100715391007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDˬHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDWDʀHrDWD4HsDWDˬHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071539100715391007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHrTDWDˬHs<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHrTDWDʀHrDWD4HsDWDˬHs<Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071540100715401007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs9(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrDWD$HsDWD(Hs9(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071540100715401007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs9(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrDWD$HsDWD(Hs9(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071540100715401007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs9(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrDWD$HsDWD(Hs9(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071540100715401007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD(Hs9(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDpHrDWD$HsDWD(Hs9(Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071541100715411007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWaDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWED8HsMPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW0DWE.DW/Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDhHrDW0DۜHrDWED8HsMPhase 3A@..DW$.12-15 YearsAYYNN. DW.DWDWAYEARSDSAC4591001C4591001 1007 10071541100715411007.DW$B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWaDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWED8HsMPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW0DWE.DW/Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDhHrDW0DۜHrDWED8HsMPhase 3A@..DW$.12-15 YearsAYYNN. DW.DWDWAYEARSDSA C4591001C4591001 1007 10071541100715411007DW0DW0B?REPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWaDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWED8HsMPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW0DWE.DW/Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDhHrDW0DۜHrDWED8HsMPhase 3A@..DW$.12-15 YearsAYYNN. DW.DWDWAYEARSDSA0C4591001C4591001 1007 10071541100715411007.DWaBpOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWaDW$YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWED8HsMPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DW0DWE.DW/Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDhHrDW0DۜHrDWED8HsMPhase 3A@..DW$.12-15 YearsAYYNN. DW.DWDWAYEARSDSA@C4591001C4591001 1007 10071542100715421007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071542100715421007.DW(B7VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071543100715431007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<Hr<DWDHHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVD<Hr<DWDHHr......Phase 3A@..DW#DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071543100715431007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD<Hr<DWDHHrPlacebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVD<Hr<DWDHHr......Phase 3A@..DW#DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071544100715441007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,Hr,DWDHrlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,Hr,DWDHrl......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071544100715441007.DW#B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD,Hr,DWDHrlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD,Hr,DWDHrl......Phase 3A@..DW#DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071546100715461007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrDWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrDWDHrP......Phase 3A@..DW#DW12-15 YearsAYYNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071546100715461007.DW#B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#DW.DW# AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrDWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrDWDHrP......Phase 3A@..DW#DW12-15 YearsAYYNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071547100715471007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrDWDHrX<DWDĤHsvbDWDHs Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071547100715471007.DW#B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrDWDHrX<DWDĤHsvbDWDHs Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071547100715471007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrDWDHrX<DWDĤHsvbDWDHs Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071547100715471007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDtHrDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDtHrDWDHrX<DWDĤHsvbDWDHs Phase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071550100715501007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDנHr4 DWDHr|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDנHr4 DWDHr|......Phase 3A@..DW$DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071550100715501007.DW$B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDנHr4 DWDHr|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDנHr4 DWDHr|......Phase 3A@..DW$DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071551100715511007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr1PDWD\HscPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr1PDWDHr/DWDHs{DWD\HscPhase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071551100715511007.DW$B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr1PDWD\HscPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr1PDWDHr/DWDHs{DWD\HscPhase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071551100715511007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr1PDWD\HscPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr1PDWDHr/DWDHs{DWD\HscPhase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071551100715511007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW$.DWDW$YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHr1PDWD\HscPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr1PDWDHr/DWDHs{DWD\HscPhase 3A@..DW$.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071552100715521007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`HrFDWDшHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`HrFDWDƄHr/DWDlHs~VlDWDшHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071552100715521007.DW#B1VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`HrFDWDшHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`HrFDWDƄHr/DWDlHs~VlDWDшHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071552100715521007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW# AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`HrFDWDшHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`HrFDWDƄHr/DWDlHs~VlDWDшHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071552100715521007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW#.DWDW#YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`HrFDWDшHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`HrFDWDƄHr/DWDlHs~VlDWDшHsPhase 3A@..DW#.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071554100715541007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrJdDWDټHr<Placebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrJdDWDټHr<......Phase 3A@..DW$DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071554100715541007.DW$B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW$DW.DW$ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrJdDWDټHr<Placebo Placebo 12-15 YearsA . . .DVDW....DWPlacebo Placebo Placebo A .Placebo A .DVDHrJdDWDټHr<......Phase 3A@..DW$DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071555100715551007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDpHrEDWD0HrG0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDpHrEDWD0HrG0......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071555100715551007.DW"B0VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW"DW.DW" AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDpHrEDWD0HrG0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDpHrEDWD0HrG0......Phase 3A@..DW"DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071557100715571007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHr*DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHr*DW DHr......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071557100715571007.DW+B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHr*DW DHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHr*DW DHr......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071558100715581007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr-|DW DLHrLBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr-|DW DLHrL......Phase 3A@..DW*DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071558100715581007.DW*B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr-|DW DLHrLBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr-|DW DLHrL......Phase 3A@..DW*DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071559100715591007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrI`DWDHs-Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrI`DW D܌Hr.DWD0HsDWDHs-Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071559100715591007.DW/B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrI`DWDHs-Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrI`DW D܌Hr.DWD0HsDWDHs-Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071559100715591007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/ AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrI`DWDHs-Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrI`DW D܌Hr.DWD0HsDWDHs-Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071559100715591007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW/.DWDW/YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrI`DWDHs-Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrI`DW D܌Hr.DWD0HsDWDHs-Phase 3A@..DW/.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071560100715601007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlLDWDHs+Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlLDW DHHr-DWD<Hsr]DWDHs+Phase 3A@..DW).12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071560100715601007.DW)B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlLDWDHs+Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlLDW DHHr-DWD<Hsr]DWDHs+Phase 3A@..DW).12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071560100715601007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlLDWDHs+Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlLDW DHHr-DWD<Hsr]DWDHs+Phase 3A@..DW).12-15 YearsAYYNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071560100715601007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlLDWDHs+Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlLDW DHHr-DWD<Hsr]DWDHs+Phase 3A@..DW).12-15 YearsAYYNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071561100715611007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrwPDW DHr%BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrwPDW DHr%......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071561100715611007.DW)B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrwPDW DHr%BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrwPDW DHr%......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071562100715621007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrB<DWDHsrIDWDHsPhase 3A@..DW(.12-15 YearsAYYNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071562100715621007.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrB<DWDHsrIDWDHsPhase 3A@..DW(.12-15 YearsAYYNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071562100715621007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrB<DWDHsrIDWDHsPhase 3A@..DW(.12-15 YearsAYYNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071562100715621007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrB<DWDHsrIDWDHsPhase 3A@..DW(.12-15 YearsAYYNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071563100715631007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlDW DHr@DWDHsrJDWDHs Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071563100715631007.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlDW DHr@DWDHsrJDWDHs Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071563100715631007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW( AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlDW DHr@DWDHsrJDWDHs Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071563100715631007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW(.DWDW(YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrlDWDHs Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrlDW DHr@DWDHsrJDWDHs Phase 3A@..DW(.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071564100715641007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHrDWDHr......Phase 3A@..DW/DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071564100715641007.DW/B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDhHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDhHrDWDHr......Phase 3A@..DW/DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071565100715651007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrDWD@Hr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrDWD@Hr@......Phase 3A@..DW/DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071565100715651007.DW/B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD8HrDWD@Hr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD8HrDWD@Hr@......Phase 3A@..DW/DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071566100715661007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrDW D4Hr;4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrDW D4Hr;4......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071566100715661007.DW(B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW(DW.DW( AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDXHrDW D4Hr;4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDXHrDW D4Hr;4......Phase 3A@..DW(DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071567100715671007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW DHr%XBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW DHr%X......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071567100715671007.DW)B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDW DHr%XBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDW DHr%X......Phase 3A@..DW)DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071568100715681007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DW DHrĆ`DWDHsDWD\HsPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071568100715681007.DW)B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DW DHrĆ`DWDHsDWD\HsPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071568100715681007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW) AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DW DHrĆ`DWDHsDWD\HsPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071568100715681007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW).DWDW)YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD`Hr`DWD\HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD`Hr`DW DHrĆ`DWDHsDWD\HsPhase 3A@..DW).12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071569100715691007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrfDWDXHsXDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071569100715691007.DW*B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrfDWDXHsXDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071569100715691007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrfDWDXHsXDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071569100715691007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW*YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDW D<HrfDWDXHsXDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071570100715701007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrPDWD0Hs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrPDW DLHreDWDHsDWD0Hs0Phase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071570100715701007.DW*B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrPDWD0Hs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrPDW DLHreDWDHsDWD0Hs0Phase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071570100715701007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrPDWD0Hs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrPDW DLHreDWDHsDWD0Hs0Phase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071570100715701007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW*YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDPHrPDWD0Hs0Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW .DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDPHrPDW DLHreDWDHsDWD0Hs0Phase 3A@..DW*.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071571100715711007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr݀BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr݀......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071571100715711007.DW*B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr݀BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr݀......Phase 3A@..DW*DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071572100715721007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD<Hr<DW DHrą4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD<Hr<DW DHrą4......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071572100715721007.DW)B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW)DW.DW) AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD<Hr<DW DHrą4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW ....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD<Hr<DW DHrą4......Phase 3A@..DW)DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071573100715731007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDXHrXDW DHr'Placebo Placebo 12-15 YearsA . . .DVDW ....DWPlacebo Placebo Placebo A .Placebo A .DVDXHrXDW DHr'......Phase 3A@..DW*DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071573100715731007.DW*B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDXHrXDW DHr'Placebo Placebo 12-15 YearsA . . .DVDW ....DWPlacebo Placebo Placebo A .Placebo A .DVDXHrXDW DHr'......Phase 3A@..DW*DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071574100715741007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr DWDHrŲBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr DWDHrŲ......Phase 3A@..DW+DW12-15 YearsAYYNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071574100715741007.DW+B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr DWDHrŲBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr DWDHrŲ......Phase 3A@..DW+DW12-15 YearsAYYNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071575100715751007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDՄHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDՄHrDWDHr......Phase 3A@..DW*DW12-15 YearsAYYNY. DW=DWDWAYEARSDSAC4591001C4591001 1007 10071575100715751007.DW*B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*DW.DW* AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDՄHrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DW>BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDՄHrDWDHr......Phase 3A@..DW*DW12-15 YearsAYYNY. DW=DWDWAYEARSDSA C4591001C4591001 1007 10071576100715761007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD4HrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DW}Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4HrDWDިHrӨDWDHslDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DW|DWDWAYEARSDSAC4591001C4591001 1007 10071576100715761007.DW*B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD4HrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DW}Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4HrDWDިHrӨDWDHslDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DW|DWDWAYEARSDSA C4591001C4591001 1007 10071576100715761007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW* AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD4HrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DW}Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4HrDWDިHrӨDWDHslDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DW|DWDWAYEARSDSA0C4591001C4591001 1007 10071576100715761007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW*.DWDW*YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVD4HrDWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DW}Placebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD4HrDWDިHrӨDWDHslDWDHsPhase 3A@..DW*.12-15 YearsA YNN. DW|DWDWAYEARSDSA@C4591001C4591001 1007 10071577100715771007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVDHr<DWDHsjO<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWuDW.DWpPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr<DWDHrDWuDHsMPDWDHsjO<Phase 3A@..DW+.12-15 YearsA YNN. DWoDWDWAYEARSDSAC4591001C4591001 1007 10071577100715771007.DW+B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVDHr<DWDHsjO<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWuDW.DWpPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr<DWDHrDWuDHsMPDWDHsjO<Phase 3A@..DW+.12-15 YearsA YNN. DWoDWDWAYEARSDSA C4591001C4591001 1007 10071577100715771007DWuDWuB}REPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVDHr<DWDHsjO<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWuDW.DWpPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr<DWDHrDWuDHsMPDWDHsjO<Phase 3A@..DW+.12-15 YearsA YNN. DWoDWDWAYEARSDSA0C4591001C4591001 1007 10071577100715771007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVDHr<DWDHsjO<Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWuDW.DWpPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHr<DWDHrDWuDHsMPDWDHsjO<Phase 3A@..DW+.12-15 YearsA YNN. DWoDWDWAYEARSDSA@C4591001C4591001 1007 10071578100715781007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD(Hr:DWDHsWpPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD(Hr:DWDLHrLDWDHs{DWDHsWpPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071578100715781007.DW+B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD(Hr:DWDHsWpPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD(Hr:DWDLHrLDWDHs{DWDHsWpPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071578100715781007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD(Hr:DWDHsWpPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD(Hr:DWDLHrLDWDHs{DWDHsWpPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071578100715781007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAMULTIPLE A`MULTIRACIAL A`YYPlacebo PLACEBO Placebo PLACEBO DVD(Hr:DWDHsWpPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVD(Hr:DWDLHrLDWDHs{DWDHsWpPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071579100715791007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr=DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr=DWDHr......Phase 3A@..DW/DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071579100715791007.DW/B7VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW/DW.DW/ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr=DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr=DWDHr......Phase 3A@..DW/DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071580100715801007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`Hr>DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`Hr>DWDHr......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071580100715801007.DW+B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVD`Hr>DWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVD`Hr>DWDHr......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071581100715811007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDlHrulDWDHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDlHrulDWDlHr$DWDdHs{dDWDHs3Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071581100715811007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDlHrulDWDHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDlHrulDWDlHr$DWDdHs{dDWDHs3Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071581100715811007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDlHrulDWDHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDlHrulDWDlHr$DWDdHs{dDWDHs3Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071581100715811007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDlHrulDWDHs3Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDlHrulDWDlHr$DWDdHs{dDWDHs3Phase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071582100715821007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrwDWDHr#BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrwDWDHr#......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071582100715821007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrwDWDHr#BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrwDWDHr#......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071583100715831007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDxHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDLHr&DWD(Hss(DWDxHsxPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071583100715831007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDxHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDLHr&DWD(Hss(DWDxHsxPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071583100715831007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDxHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDLHr&DWD(Hss(DWDxHsxPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071583100715831007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWDxHsxPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWDLHr&DWD(Hss(DWDxHsxPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071584100715841007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr}DWDHr*PBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr}DWDHr*P......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071584100715841007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHr}DWDHr*PBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHr}DWDHr*P......Phase 3A@..DW+DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071585100715851007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHr~TDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHr~TDWDHr'DWDHsr@DWDHslPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071585100715851007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHr~TDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHr~TDWDHr'DWDHsr@DWDHslPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071585100715851007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHr~TDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHr~TDWDHr'DWDHsr@DWDHslPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071585100715851007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDTHr~TDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDTHr~TDWDHr'DWDHsr@DWDHslPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071586100715861007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hr$DWDHsDWD HsPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071586100715861007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hr$DWDHsDWD HsPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071586100715861007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+ AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hr$DWDHsDWD HsPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071586100715861007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW+.DWDW+YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DVDHrDWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DVDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADVDHrDWD0Hr$DWDHsDWD HsPhase 3A@..DW+.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071587100715871007DVDVASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA ASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr+@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr+@......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071587100715871007.DW+B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW+DW.DW+ AYEARSFA ASIAN A@ASIAN A@YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DVDHrDWDHr+@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DVDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DVDHrDWDHr+@......Phase 3A@..DW+DW12-15 YearsAYYNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071588100715881007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWD@Hr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWD@Hr@......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071588100715881007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWD@Hr@BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWD@Hr@......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071589100715891007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDǰHsðPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDHHr֢DWDHssDWDǰHsðPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071589100715891007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDǰHsðPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDHHr֢DWDHssDWDǰHsðPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071589100715891007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDǰHsðPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDHHr֢DWDHssDWDǰHsðPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071589100715891007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDǰHsðPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDHHr֢DWDHssDWDǰHsðPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071590100715901007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr,DWDlHrHlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr,DWDlHrHl......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071590100715901007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr,DWDlHrHlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr,DWDlHrHl......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071591100715911007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr`DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr`DWDHr֛HDWDHsb DWDHsPhase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071591100715911007.DW>B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr`DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr`DWDHr֛HDWDHsb DWDHsPhase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071591100715911007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr`DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr`DWDHr֛HDWDHsb DWDHsPhase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071591100715911007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW>YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr`DWDHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr`DWDHr֛HDWDHsb DWDHsPhase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071592100715921007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDxHrDWD\Hr֝BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDxHrDWD\Hr֝......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071592100715921007.DW?B;VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDxHrDWD\Hr֝BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDxHrDWD\Hr֝......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071593100715931007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED ...DWY AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr͜DWDHr͜Placebo Placebo 12-15 YearsA . . .DW.....DW3Placebo Placebo A .Placebo A .DWDHr͜DWDHr͜......Phase 3A@DW3DW..12-15 YearsA YNN. DW2DW3DW3AYEARSDSAC4591001C4591001 1007 10071593100715931007.DWBVACCINATION BDISPOSITION EVENTPROTOCOL DEVIATION Areceipt of non-study COVID vaccine prior to study end ...DWY AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr͜DWDHr͜Placebo Placebo 12-15 YearsA . . .DW.....DW3Placebo Placebo A .Placebo A .DWDHr͜DWDHr͜......Phase 3A@DW3DW..12-15 YearsA YNN. DW2DW3DW3AYEARSDSA0C4591001C4591001 1007 10071593100715931007.DW3B/FOLLOW-UP BDISPOSITION EVENTPROTOCOL DEVIATION AReceipt of non-study COVID vaccine prior to study end ...DWY AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr͜DWDHr͜Placebo Placebo 12-15 YearsA . . .DW.....DW3Placebo Placebo A .Placebo A .DWDHr͜DWDHr͜......Phase 3A@DW3DW..12-15 YearsA YNN. DW2DW3DW3AYEARSDSA@C4591001C4591001 1007 10071594100715941007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrLDWDHrdBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrLDWDHrd......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071594100715941007.DW=B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrLDWDHrdBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrLDWDHrd......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071595100715951007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDИHrDWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDИHrDWDHrֱPDWD$Hss$DWDHs|Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071595100715951007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDИHrDWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDИHrDWDHrֱPDWD$Hss$DWDHs|Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071595100715951007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDИHrDWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDИHrDWDHrֱPDWD$Hss$DWDHs|Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071595100715951007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDИHrDWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDИHrDWDHrֱPDWD$Hss$DWDHs|Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071596100715961007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs5tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDpHrDpDWDHs{DWDHs5tPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071596100715961007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs5tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDpHrDpDWDHs{DWDHs5tPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071596100715961007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs5tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDpHrDpDWDHs{DWDHs5tPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071596100715961007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs5tPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDpHrDpDWDHs{DWDHs5tPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071597100715971007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD$HrDWDXHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD$HrDWDXHr......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071597100715971007.DW>B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD$HrDWDXHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD$HrDWDXHr......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071599100715991007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD`HrDWD(Hr¨BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD`HrDWD(Hr¨......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071599100715991007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD`HrDWD(Hr¨BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD`HrDWD(Hr¨......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071600100716001007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDPHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDPHrDWD8HrDWDlHslDWDHs(Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071600100716001007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDPHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDPHrDWD8HrDWDlHslDWDHs(Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071600100716001007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDPHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDPHrDWD8HrDWDlHslDWDHs(Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071600100716001007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDPHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDPHrDWD8HrDWDlHslDWDHs(Phase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071601100716011007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWSDW.DWS AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHr(DWD4HrPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHr(DWD4Hr......Phase 3A@..DWSDW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071601100716011007.DWSBOVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWSDW.DWS AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHr(DWD4HrPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHr(DWD4Hr......Phase 3A@..DWSDW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071602100716021007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWD HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWD Hr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071602100716021007.DW8B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWD HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWD Hr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071603100716031007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHr Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHrDWDHr ......Phase 3A@..DW>DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071603100716031007.DW>B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHr Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHrDWDHr ......Phase 3A@..DW>DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071604100716041007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHr,Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHrDWDHr,......Phase 3A@..DW8DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071604100716041007.DW8B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHr,Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHrDWDHr,......Phase 3A@..DW8DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071605100716051007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD\Hr\DWDHr֥\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD\Hr\DWDHr֥\......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071605100716051007.DW>B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD\Hr\DWDHr֥\BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD\Hr\DWDHr֥\......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071606100716061007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWGDW.DWG AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDDHrDDWDpHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDDHrDDWDpHr......Phase 3A@..DWGDW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071606100716061007.DWGBBVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWGDW.DWG AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDDHrDDWDpHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDDHrDDWDpHr......Phase 3A@..DWGDW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071607100716071007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD4Hr44DWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD4Hr44DWDHr DWDHssDWD8HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071607100716071007.DW?B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD4Hr44DWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD4Hr44DWDHr DWDHssDWD8HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071607100716071007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD4Hr44DWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD4Hr44DWDHr DWDHssDWD8HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071607100716071007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD4Hr44DWD8HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD4Hr44DWDHr DWDHssDWD8HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071608100716081007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr2DWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr2DWDTHrDWDHssDWD HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071608100716081007.DW?B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr2DWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr2DWDTHrDWDHssDWD HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071608100716081007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr2DWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr2DWDTHrDWDHssDWD HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071608100716081007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr2DWD HsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr2DWDTHrDWDHssDWD HsPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071609100716091007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD\Hr9\DWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD\Hr9\DWDHrH......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071609100716091007.DW=B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD\Hr9\DWDHrHBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD\Hr9\DWDHrH......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071610100716101007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSFA AMERICAN INDIAN OR ALASKA NATIVE A0AMERICAN INDIAN OR ALASKA NATIVE A0YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr=DWDHrٜBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DW}BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr=DWDHrٜ......Phase 3A@..DW9DW12-15 YearsA YNY. DW|DWDWAYEARSDSAC4591001C4591001 1007 10071610100716101007.DW9B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSFA AMERICAN INDIAN OR ALASKA NATIVE A0AMERICAN INDIAN OR ALASKA NATIVE A0YYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr=DWDHrٜBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DW}BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr=DWDHrٜ......Phase 3A@..DW9DW12-15 YearsA YNY. DW|DWDWAYEARSDSA C4591001C4591001 1007 10071612100716121007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr;DWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr;DWDHrP......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071612100716121007.DW@B;VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHr;DWDHrPBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHr;DWDHrP......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071613100716131007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD HrM DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD HrM DWDϨHr(DWDHs|4DWDHslPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071613100716131007.DW8B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD HrM DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD HrM DWDϨHr(DWDHs|4DWDHslPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071613100716131007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD HrM DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD HrM DWDϨHr(DWDHs|4DWDHslPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071613100716131007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD HrM DWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD HrM DWDϨHr(DWDHs|4DWDHslPhase 3A@..DW8.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071614100716141007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD`HrS`DWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD`HrS`DWDHrDWD,Hsvq,DWDHs|Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071614100716141007.DW>B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD`HrS`DWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD`HrS`DWDHrDWD,Hsvq,DWDHs|Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071614100716141007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD`HrS`DWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD`HrS`DWDHrDWD,Hsvq,DWDHs|Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071614100716141007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW>YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD`HrS`DWDHs|Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD`HrS`DWDHrDWD,Hsvq,DWDHs|Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071615100716151007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrLDWDHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrLDWDHrx......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071615100716151007.DW>B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrLDWDHrxBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrLDWDHrx......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071616100716161007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDDHrQDDWDôHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDDHrQDDWDôHr4......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071616100716161007.DW>B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDDHrQDDWDôHr4BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDDHrQDDWDôHr4......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071617100716171007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDXHr[XDWDHsi^Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWuDW.DWjPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDXHr[XDWDhHrLhDWuDhHsMGDWDHsi^Phase 3A@..DW8.12-15 YearsA YNN. DWiDWDWAYEARSDSAC4591001C4591001 1007 10071617100716171007.DW8B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDXHr[XDWDHsi^Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWuDW.DWjPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDXHr[XDWDhHrLhDWuDhHsMGDWDHsi^Phase 3A@..DW8.12-15 YearsA YNN. DWiDWDWAYEARSDSA C4591001C4591001 1007 10071617100716171007DWuDWuBpREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8 AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDXHr[XDWDHsi^Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWuDW.DWjPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDXHr[XDWDhHrLhDWuDhHsMGDWDHsi^Phase 3A@..DW8.12-15 YearsA YNN. DWiDWDWAYEARSDSA0C4591001C4591001 1007 10071617100716171007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW8.DWDW8YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDXHr[XDWDHsi^Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWuDW.DWjPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDXHr[XDWDhHrLhDWuDhHsMGDWDHsi^Phase 3A@..DW8.12-15 YearsA YNN. DWiDWDWAYEARSDSA@C4591001C4591001 1007 10071618100716181007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr[DWD0Hr֜Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHr[DWD0Hr֜......Phase 3A@..DW?DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071618100716181007.DW?B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr[DWD0Hr֜Placebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWDHr[DWD0Hr֜......Phase 3A@..DW?DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071619100716191007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrCDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrCDWDHr......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071619100716191007.DW?B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrCDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrCDWDHr......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071620100716201007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrM8DWDHrRBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrM8DWDHrR......Phase 3A@..DW9DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071620100716201007.DW9B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrM8DWDHrRBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrM8DWDHrR......Phase 3A@..DW9DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071621100716211007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD,HrQDWDHrRPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWD,HrQDWDHrR......Phase 3A@..DW9DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071621100716211007.DW9B3VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWD,HrQDWDHrRPlacebo Placebo 12-15 YearsA . . .DWDW....DWPlacebo Placebo Placebo A .Placebo A .DWD,HrQDWDHrR......Phase 3A@..DW9DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071622100716221007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW9DW.DW9 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrPDDWDHrPDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW.....DW6BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrPDDWDHrPD......Phase 3A@.DWDW9DW12-15 YearsA YNN. DW5DWDWAYEARSDSAC4591001C4591001 1007 10071622100716221007.DWBVACCINATION BDISPOSITION EVENTOTHER ApParticipant had COVID-19 prior to second vaccine DW9DW.DW9 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrPDDWDHrPDBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW.....DW6BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrPDDWDHrPD......Phase 3A@.DWDW9DW12-15 YearsA YNN. DW5DWDWAYEARSDSA0C4591001C4591001 1007 10071623100716231007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDtHrTDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDtHrTDWDTHr٢DWDHsLDWDHslPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071623100716231007.DW?B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDtHrTDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDtHrTDWDTHr٢DWDHsLDWDHslPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071623100716231007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDtHrTDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDtHrTDWDTHr٢DWDHsLDWDHslPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071623100716231007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDtHrTDWDHslPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDtHrTDWDTHr٢DWDHsLDWDHslPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071624100716241007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHre DWD4Hs$4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHre DW"DdHrdDWDHsuXDWD4Hs$4Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071624100716241007.DW>B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHre DWD4Hs$4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHre DW"DdHrdDWDHsuXDWD4Hs$4Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071624100716241007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHre DWD4Hs$4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHre DW"DdHrdDWDHsuXDWD4Hs$4Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071624100716241007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW>YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHre DWD4Hs$4Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHre DW"DdHrdDWDHsuXDWD4Hs$4Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071625100716251007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrg<DWDHs"Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrg<DW"DtHrtDWD$HsuDWDHs"Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071625100716251007.DW>B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrg<DWDHs"Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrg<DW"DtHrtDWD$HsuDWDHs"Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071625100716251007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrg<DWDHs"Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrg<DW"DtHrtDWD$HsuDWDHs"Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071625100716251007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW>YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHrg<DWDHs"Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW".DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrg<DW"DtHrtDWD$HsuDWDHs"Phase 3A@..DW>.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071626100716261007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD HrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD HrDWDHr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071626100716261007.DW8B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD HrDWDHrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD HrDWDHr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071627100716271007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD̜HrDWD~HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD̜HrDWD~Hr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071627100716271007.DW8B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW8DW.DW8 AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWD̜HrDWD~HrBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWD̜HrDWD~Hr......Phase 3A@..DW8DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071628100716281007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDXHrDWDƄHr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDXHrDWDƄHr0......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071628100716281007.DW=B7VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDXHrDWDƄHr0BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDXHrDWDƄHr0......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071629100716291007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWD|HrDWDHsτPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD|HrDWD@Hr@DWD̜Hs<DWDHsτPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071629100716291007.DW?B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWD|HrDWDHsτPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD|HrDWD@Hr@DWD̜Hs<DWDHsτPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071629100716291007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWD|HrDWDHsτPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD|HrDWD@Hr@DWD̜Hs<DWDHsτPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071629100716291007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSFA ASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWD|HrDWDHsτPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWD|HrDWD@Hr@DWD̜Hs<DWDHsτPhase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071630100716301007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDHrDWDHs>DWDHs(Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071630100716301007.DW?B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDHrDWDHs>DWDHs(Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071630100716301007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDHrDWDHs>DWDHs(Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071630100716301007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DWDHrDWDHs(Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHrDWDHrDWDHs>DWDHs(Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071631100716311007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWDHrٝpBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWDHrٝp......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071631100716311007.DW@B:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWDHrٝpBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWDHrٝp......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071632100716321007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDHs9Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDlHr]DWDPHssPDWDHs9Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071632100716321007.DW?B9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDHs9Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDlHr]DWDPHssPDWDHs9Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071632100716321007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW? AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDHs9Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDlHr]DWDPHssPDWDHs9Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071632100716321007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW?.DWDW?YAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DWDHr DWDHs9Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DWDW.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADWDHr DWDlHr]DWDPHssPDWDHs9Phase 3A@..DW?.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071633100716331007DWDWASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWDHr٠|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWDHr٠|......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071633100716331007.DW>B8VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>DW.DW> AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DWDHrDWDHr٠|BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DWDW....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DWDHrDWDHr٠|......Phase 3A@..DW>DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071634100716341007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrDW!DHrޜlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrDW!DHrޜl......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071634100716341007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrDW!DHrޜlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrDW!DHrޜl......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071635100716351007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=..DW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!DHrPPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!DHrP......Phase 3A@DW.DW=.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071635100716351007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=..DW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!DHrPPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!DHrP......Phase 3A@DW.DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071635100716351007.DWBFOLLOW-UP BDISPOSITION EVENTWITHDRAWAL BY SUBJECT BPfizer vaccine outside of study, participant verbalized wanting to withdrawal from the study DW=..DW=YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!DHrPPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!DHrP......Phase 3A@DW.DW=.12-15 YearsA YNN. DWDWDWAYEARSDSApC4591001C4591001 1007 10071636100716361007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrDW!DHrގ BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrDW!DHrގ ......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071636100716361007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrDW!DHrގ BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrDW!DHrގ ......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071638100716381007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D<Hr<DW!DHrއBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D<Hr<DW!DHrއ......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071638100716381007.DW?B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D<Hr<DW!DHrއBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D<Hr<DW!DHrއ......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071639100716391007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWD..DWD AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!D4HrށPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!D4Hrށ......Phase 3A@DW.DWD.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071639100716391007.DWDB9VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWD..DWD AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!D4HrށPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!D4Hrށ......Phase 3A@DW.DWD.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071639100716391007.DWBFOLLOW-UP BDISPOSITION EVENTWITHDRAWAL BY PARENT/GUARDIAN BParticipant Moving DWD..DWDYAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDW!D4HrށPlacebo Placebo 12-15 YearsA . . .DW DW!....DWPlacebo Placebo Placebo A .Placebo A .DW DHrDW!D4Hrށ......Phase 3A@DW.DWD.12-15 YearsA YNN. DWDWDWAYEARSDSApC4591001C4591001 1007 10071640100716401007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DWE.DWDWE AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDWDhHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHrDW!DHr@DWDHsDWDhHsPhase 3A@..DWE.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071640100716401007.DWEB:VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DWE.DWDWE AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDWDhHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHrDW!DHr@DWDHsDWDhHsPhase 3A@..DWE.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071640100716401007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DWE.DWDWE AYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDWDhHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHrDW!DHr@DWDHsDWDhHsPhase 3A@..DWE.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071640100716401007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DWE.DWDWEYAYEARSFA WHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHrDWDhHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHrDW!DHr@DWDHsDWDhHsPhase 3A@..DWE.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071641100716411007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D(Hr(DW"DHr-BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW"....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D(Hr(DW"DHr-......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071641100716411007.DW?B4VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW?DW.DW? AYEARSFA WHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D(Hr(DW"DHr-BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW"....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D(Hr(DW"DHr-......Phase 3A@..DW?DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071642100716421007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D,Hr%,DWDθHs8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW .DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D,Hr%,DWDθHs8......Phase 3A@..DW=DW12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071642100716421007.DWBVACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW D,Hr%,DWDθHs8BNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW .DW...DWBNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW D,Hr%,DWDθHs8......Phase 3A@..DW=DW12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071643100716431007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHr#DWDHs`Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr#DW!DHrlDWDИHsDWDHs`Phase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071643100716431007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHr#DWDHs`Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr#DW!DHrlDWDИHsDWDHs`Phase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071643100716431007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHr#DWDHs`Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr#DW!DHrlDWDИHsDWDHs`Phase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071643100716431007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW=YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW DHr#DWDHs`Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr#DW!DHrlDWDИHsDWDHs`Phase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071644100716441007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DpHr;pDW!DHrhBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DpHr;pDW!DHrh......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071644100716441007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=DW.DW= AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DpHr;pDW!DHrhBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DpHr;pDW!DHrh......Phase 3A@..DW=DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071645100716451007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D(Hr8(DWDHsȄPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D(Hr8(DW!DHr4DWDHs~.DWDHsȄPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071645100716451007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D(Hr8(DWDHsȄPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D(Hr8(DW!DHr4DWDHs~.DWDHsȄPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071645100716451007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D(Hr8(DWDHsȄPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D(Hr8(DW!DHr4DWDHs~.DWDHsȄPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071645100716451007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW=YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D(Hr8(DWDHsȄPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D(Hr8(DW!DHr4DWDHs~.DWDHsȄPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071646100716461007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D,HrC,DWDTHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D,HrC,DW!DLHrDWDPHsPDWDTHsPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSAC4591001C4591001 1007 10071646100716461007.DW=B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D,HrC,DWDTHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D,HrC,DW!DLHrDWDPHsPDWDTHsPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA C4591001C4591001 1007 10071646100716461007DWDWBREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW= AYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D,HrC,DWDTHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D,HrC,DW!DLHrDWDPHsPDWDTHsPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA0C4591001C4591001 1007 10071646100716461007.DWBOPEN LABEL TREATMENTApDISPOSITION EVENTCOMPLETED A COMPLETED DW=.DWDW=YAYEARSMAWHITE AWHITE AYYPlacebo PLACEBO Placebo PLACEBO DW D,HrC,DWDTHsPlacebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW!.DWDW.DWPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW D,HrC,DW!DLHrDWDPHsPDWDTHsPhase 3A@..DW=.12-15 YearsA YNN. DWDWDWAYEARSDSA@C4591001C4591001 1007 10071647100716471007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrEDW!DHrlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrEDW!DHrl......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSAC4591001C4591001 1007 10071647100716471007.DW@B5VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW@DW.DW@ AYEARSMAWHITE AWHITE AYYBNT162b2 Phase 2/3 (30 mcg)B2_P23_30BNT162b2 Phase 2/3 (30 mcg)B2_P23_30DW DHrEDW!DHrlBNT162b2 Phase 2/3 (30 mcg) BNT162b2 Phase 2/3 (30 mcg) 12-15 YearsA . . .DW DW!....DWBNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) BNT162b2 Phase 2/3 (30 mcg)A .BNT162b2 Phase 2/3 (30 mcg)A .DW DHrEDW!DHrl......Phase 3A@..DW@DW12-15 YearsA YNY. DWDWDWAYEARSDSA C4591001C4591001 1007 10071648100716481007DW DW ASCREENING ADISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DW DHr(dDWDHsji@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW".DWvDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr(dDW"DHrDWvDHsN¨DWDHsji@Phase 3A@..DW>.12-15 YearsA YNN. DWtDWDWAYEARSDSAC4591001C4591001 1007 10071648100716481007.DW>B2VACCINATION BDISPOSITION EVENTCOMPLETED A COMPLETED DW>.DWDW> AYEARSMAASIAN A@ASIAN A@YYPlacebo PLACEBO Placebo PLACEBO DW DHr(dDWDHsji@Placebo => BNT162b2 Phase 2/3 (30 mcg)Placebo => BNT162b2 Phase 2/3 (30 mcg)12-15 YearsA . . .DW DW".DWvDW.DWuPlacebo Placebo BNT162b2 (30 (*ESC*){unicode 03BC}g)BNT162b2 (30 (*ESC*){unicode 03BC}g) Placebo ABNT162b2 Phase 2/3 (30 mcg)APlacebo ABNT162b2 Phase 2/3 (30 mcg)ADW DHr(dDW"DHrDWvDHsN¨DWDHsji@Phase 3A@..DW>.12-15 YearsA YNN. DWtDWDWAYEARSDSA C4591001C4591001 1007 10071648100716481007DWvDWvBjREPEAT SCREENING 1 BeDISPOSITION EVENTCOMPLETED A COMPLETED