HEADER RECORD*******LIBRARY HEADER RECORD!!!!!!!000000000000000000000000000000 SAS SAS SASLIB 9.4 Linux 31MAR21:12:06:0331MAR21:12:06:03 HEADER RECORD*******MEMBER HEADER RECORD!!!!!!!000000000000000001600000000140 HEADER RECORD*******DSCRPTR HEADER RECORD!!!!!!!000000000000000000000000000000 SAS IE SASDATA 9.4 Linux 31MAR21:12:06:0331MAR21:12:06:03 Inclusion/Exclusion Criteria Not Met HEADER RECORD*******NAMESTR HEADER RECORD!!!!!!!000000001500000000000000000000 STUDYID Study Identifier DOMAIN Domain Abbreviation USUBJID Unique Subject Identifier IESEQ Sequence Number IESPID Sponsor-Defined Identifier (IETESTCDInclusion/Exclusion Criterion Short Name *ÈIETEST Inclusion/Exclusion Criterion 1 IECAT Inclusion/Exclusion Category ù IEORRES I/E Criterion Original Result  IESTRESCI/E Criterion Result in Std Format  VISITNUMVisit Number  VISIT Visit Name   EPOCH Epoch ! IEDTC Date/Time of Collection 5IEDY Study Day of Collection ? HEADER RECORD*******OBS HEADER RECORD!!!!!!!000000000000000000000000000000 C4591001IEC4591001 1001 10011001A18EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-04-30.C4591001IEC4591001 1001 10011003A20EX20A00Sentinel participants in Stage 1 only: SARS-CoV-2 NAAT-positive nasal swab within 24 hours before receipt of study intervention EXCLUSIONYYDíKSCR SCREENING 2020-05-01.C4591001IEC4591001 1001 10011010A20EX20A00Sentinel participants in Stage 1 only: SARS-CoV-2 NAAT-positive nasal swab within 24 hours before receipt of study intervention EXCLUSIONYYDíKSCR SCREENING 2020-05-05.C4591001IEC4591001 1001 10011016A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-06.C4591001IEC4591001 1001 10011022A17EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-05-08.C4591001IEC4591001 1001 10011023A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-11.C4591001IEC4591001 1001 10011025A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-05-12.C4591001IEC4591001 1001 10011029A18EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-05-14.C4591001IEC4591001 1001 10011035A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-05-15.C4591001IEC4591001 1001 10011035A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-15.C4591001IEC4591001 1001 10011036A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-01.C4591001IEC4591001 1001 10011038A9 EX09A00Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDíKSCR SCREENING 2020-06-01.C4591001IEC4591001 1001 10011047A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1001 10011047A 4 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1001 10011051A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDíKSCR SCREENING 2020-06-10.C4591001IEC4591001 1001 10011051A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-10.C4591001IEC4591001 1001 10011054A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1001 10011056A20EX19A00Sentinel participants in Stage 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1001 10011060A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1001 10011060A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1001 10011062A18EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1001 10011065A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-16.C4591001IEC4591001 1001 10011065A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-16.C4591001IEC4591001 1001 10011072A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDíKSCR SCREENING 2020-06-24.C4591001IEC4591001 1001 10011073A18EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-24.C4591001IEC4591001 1001 10011074A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-24.C4591001IEC4591001 1001 10011075A20EX19A00Sentinel participants in Stage 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-24.C4591001IEC4591001 1001 10011079A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-29.C4591001IEC4591001 1001 10011080A18EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-29.C4591001IEC4591001 1001 10011128A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1001 10011140A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1002 10021001A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDíKSCR SCREENING 2020-04-29.C4591001IEC4591001 1002 10021001A 18EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-04-29.C4591001IEC4591001 1002 10021002A18EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-04-29.C4591001IEC4591001 1002 10021010A19EX19A00Sentinel participants in Stage 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDíKSCR SCREENING 2020-04-30.C4591001IEC4591001 1002 10021046A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-05-29.C4591001IEC4591001 1002 10021046A18EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-05-29.C4591001IEC4591001 1002 10021048A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-06-01.C4591001IEC4591001 1002 10021048A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-01.C4591001IEC4591001 1002 10021051A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1002 10021053A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-03Á€C4591001IEC4591001 1002 10021055A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1002 10021056A6 EX06A01Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 (full details in protocol) EXCLUSIONYYDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1002 10021056A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1002 10021057A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-04.C4591001IEC4591001 1002 10021058A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-04.C4591001IEC4591001 1002 10021061A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1002 10021065A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-09.C4591001IEC4591001 1002 10021066A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-09.C4591001IEC4591001 1002 10021070A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-10.C4591001IEC4591001 1002 10021076A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1002 10021078A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1002 10021086A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-23.C4591001IEC4591001 1003 10031011A19EX19A00Sentinel participants in Stage 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDíKSCR SCREENING 2020-05-06.C4591001IEC4591001 1003 10031012A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-06.C4591001IEC4591001 1003 10031017A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-01Á C4591001IEC4591001 1003 10031021A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-02ÁpC4591001IEC4591001 1003 10031033A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031039A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031040A6 EX06A01Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 (full details in protocol) EXCLUSIONYYDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031041A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031041A9 EX09A00Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031042A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031044A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-05.C4591001IEC4591001 1003 10031047A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-08Á€C4591001IEC4591001 1003 10031048A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1003 10031049A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1003 10031052A9 EX09A00Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1003 10031060A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1003 10031062A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1003 10031064A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-12.C4591001IEC4591001 1003 10031068A20EX19A00Sentinel participants in Stage 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1003 10031070A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-18Á`C4591001IEC4591001 1003 10031073A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-19.C4591001IEC4591001 1003 10031074A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-22.C4591001IEC4591001 1003 10031081A9 EX09A00Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDíKSCR SCREENING 2020-06-25.C4591001IEC4591001 1003 10031084A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-25.C4591001IEC4591001 1003 10031085A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-25.C4591001IEC4591001 1003 10031140A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04AC4591001IEC4591001 1003 10031143A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04AC4591001IEC4591001 1005 10051099A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1005 10051133A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1005 10051140A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1005 10051190A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1005 10051279A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1005 10051297A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1005 10051376A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1005 10051383A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1005 10051388A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1005 10051404A IN01A07Male or female participants between 18 and 55 years inclusive and 65 and 85 years inclusive (Phase 1) or >= 12 years (Phase 2/3) at randomization. Participants <18 years cannot be enrolled in EU INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-05.C4591001IEC4591001 1006 10061026A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1006 10061038A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1006 10061042A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1006 10061048A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1006 10061072A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1006 10061087A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1006 10061099A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24AC4591001IEC4591001 1006 10061126A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1006 10061127A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1006 10061161A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-01-15BqC4591001IEC4591001 1006 10061172A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1006 10061172A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1006 10061175A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1006 10061198A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-03.C4591001IEC4591001 1006 10061246A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-10AC4591001IEC4591001 1006 10061251A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-11.C4591001IEC4591001 1006 10061268A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-15.C4591001IEC4591001 1006 10061272A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-16AC4591001IEC4591001 1006 10061281A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-18.C4591001IEC4591001 1007 10071001A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-04.C4591001IEC4591001 1007 10071009A6 EX06A00Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 EXCLUSIONYYDíKSCR SCREENING 2020-05-04.C4591001IEC4591001 1007 10071010A9 EX09A00Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDíKSCR SCREENING 2020-05-06.C4591001IEC4591001 1007 10071013A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-02.C4591001IEC4591001 1007 10071018A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-02.C4591001IEC4591001 1007 10071024A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1007 10071028A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-03.C4591001IEC4591001 1007 10071030A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1007 10071033A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1007 10071036A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDíKSCR SCREENING 2020-06-08.C4591001IEC4591001 1007 10071041A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-10.C4591001IEC4591001 1007 10071047A6 EX06A01Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 (full details in protocol) EXCLUSIONYYDíKSCR SCREENING 2020-06-11.C4591001IEC4591001 1007 10071048A18EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-11.C4591001IEC4591001 1007 10071054A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071055A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071059A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071059A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071060A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071062A18EX17A00Sentinel participants in Stage 1 only: Positive serological test for SARS-CoV-2 IgM and/or IgG antibodies at the screening visit EXCLUSIONYYDíKSCR SCREENING 2020-06-15.C4591001IEC4591001 1007 10071069A6 EX06A01Sentinel participants in Stage 1 only: Individuals at high risk for severe COVID-19 (full details in protocol) EXCLUSIONYYDíKSCR SCREENING 2020-06-18.C4591001IEC4591001 1007 10071072A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-22.C4591001IEC4591001 1007 10071076A19EX18A00Sentinel participants in Stage 1 only: Screening hematology/blood chemistry lab >=Grade 1 abnormality. Except Bilirubin, other stable Grade1 abnormalities may be considered eligible by Investigator EXCLUSIONYYDíKSCR SCREENING 2020-06-22.C4591001IEC4591001 1007 10071078A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDíKSCR SCREENING 2020-06-24.C4591001IEC4591001 1007 10071170A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1007 10071202A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1007 10071247A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1007 10071282A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1007 10071290A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1007 10071331A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1007 10071361A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1007 10071394A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1007 10071395A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1007 10071413A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1007 10071453A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-12.C4591001IEC4591001 1007 10071545A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-10.C4591001IEC4591001 1007 10071598A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-28.C4591001IEC4591001 1007 10071637A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-04.C4591001IEC4591001 1007 10071657A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-06.C4591001IEC4591001 1008 10081124A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1008 10081759A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-03.C4591001IEC4591001 1008 10081939A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-11.C4591001IEC4591001 1009 10091033A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1009 10091083A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1009 10091137A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1009 10091150A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1009 10091152A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1009 10091215A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1009 10091245A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1009 10091248A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1009 10091251A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1009 10091268A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-01.C4591001IEC4591001 1009 10091302A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-07.C4591001IEC4591001 1009 10091327A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-11.C4591001IEC4591001 1009 10091352A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-16.C4591001IEC4591001 1009 10091367A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-17.C4591001IEC4591001 1009 10091368A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-17.C4591001IEC4591001 1009 10091397A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2021-01-07.C4591001IEC4591001 1011 10111003A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1011 10111010A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1011 10111103A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1011 10111110A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1011 10111112A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1011 10111160A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1011 10111165A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1011 10111205A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1011 10111207A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1012 10121012A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1012 10121012A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1012 10121017A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1012 10121019A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1012 10121019A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1012 10121052A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1013 10131075A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1013 10131088A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1013 10131160A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1013 10131160A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1013 10131164A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1013 10131208A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1013 10131233A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1013 10131547A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1013 10131577A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1013 10131610A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1013 10131631A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1013 10131649A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1013 10131659A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1013 10131674A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1013 10131674A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1013 10131704A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1013 10131711A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1013 10131732A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1013 10131788A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1016 10161072A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1016 10161104A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1016 10161121A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1016 10161150A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1016 10161182A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1016 10161219A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1016 10161227A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1016 10161246A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1016 10161250A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1016 10161251A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1016 10161380A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2021-01-07.C4591001IEC4591001 1018 10181008A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-29.C4591001IEC4591001 1018 10181008A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-29.C4591001IEC4591001 1018 10181044A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1018 10181082A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1018 10181121A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1018 10181129A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1018 10181130A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1018 10181130A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1018 10181135A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1018 10181172A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1018 10181203A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181209A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181209A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181210A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181210A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181210A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1018 10181217A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1018 10181229A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1018 10181253A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1018 10181258A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1018 10181271A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1018 10181273A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1018 10181318A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1018 10181319A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2020-12-16BAC4591001IEC4591001 1018 10181325A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1018 10181325A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1018 10181330A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1018 10181331A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1018 10181343A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1018 10181350A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1019 10191114A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1019 10191115A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1019 10191149A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1019 10191183A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1019 10191185A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1019 10191203A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1019 10191294A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1019 10191300A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22AC4591001IEC4591001 1022 10221016A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1022 10221072A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1022 10221113A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1022 10221130A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1022 10221135A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1022 10221159A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1022 10221172A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1024 10241025A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1024 10241035A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1024 10241047A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1024 10241103A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1027 10271210A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1028 10281071A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1028 10281136A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1028 10281219A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1028 10281238A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1028 10281260A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1028 10281260A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1028 10281263A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1028 10281281A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1030 10301117A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1030 10301129A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1036 10361024A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1036 10361037A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1036 10361050A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31AC4591001IEC4591001 1036 10361136A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1037 10371021A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1037 10371025A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1037 10371035A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1037 10371057A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24AC4591001IEC4591001 1037 10371118A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1037 10371150A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1037 10371204A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1037 10371225A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1037 10371247A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1037 10371326A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1037 10371333A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09AC4591001IEC4591001 1037 10371346A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1037 10371348A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1038 10381039A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1038 10381039A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1038 10381039A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1038 10381071A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1038 10381071A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1038 10381087A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1038 10381092A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1038 10381106A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1038 10381106A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1038 10381106A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1039 10391048A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1039 10391063A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1039 10391066A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1039 10391121A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1039 10391149A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1039 10391161A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-29.C4591001IEC4591001 1039 10391191A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1039 10391194A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1039 10391195A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1039 10391204A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1039 10391210A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1039 10391215A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1039 10391219A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1039 10391223A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1039 10391236A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1042 10421005A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1042 10421006A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1042 10421007A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1042 10421012A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1042 10421015A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1042 10421016A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1042 10421019A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1042 10421030A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1042 10421042A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1042 10421046A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1042 10421047A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1042 10421049A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1042 10421053A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1042 10421094A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1042 10421096A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1042 10421136A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1042 10421137A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1042 10421149A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1042 10421184A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1042 10421199A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1042 10421201A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1042 10421248A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1042 10421257A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1044 10441097A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1044 10441118A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1044 10441130A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1044 10441152A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28AC4591001IEC4591001 1044 10441183A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1046 10461103A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1046 10461189A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1046 10461228A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1047 10471004A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1047 10471007A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1047 10471044A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1047 10471050A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1047 10471122A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03AC4591001IEC4591001 1047 10471196A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-12.C4591001IEC4591001 1047 10471228A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16AC4591001IEC4591001 1048 10481059A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1048 10481076A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1054 10541004A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1054 10541010A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1054 10541020A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1054 10541029A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1054 10541033A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22AC4591001IEC4591001 1054 10541040A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1054 10541110A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2020-12-28BuC4591001IEC4591001 1054 10541117A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1054 10541147A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1054 10541162A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1054 10541172A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1054 10541189A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1056 10561012A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1056 10561033A0 IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1056 10561033A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1056 10561033A EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1056 10561054A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1056 10561094A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1056 10561094A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1056 10561117A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1056 10561138A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1056 10561142A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1056 10561166A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1056 10561216A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1056 10561223A0 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561223A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561223A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561224A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561224A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561225A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561225A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1056 10561250A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1056 10561279A0 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1056 10561279A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1056 10561279A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1056 10561297A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1056 10561318A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1056 10561323A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1056 10561323A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1056 10561326A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1056 10561326A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1056 10561328A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1056 10561329A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1056 10561346A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1056 10561356A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1056 10561357A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1056 10561431A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1056 10561435A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1056 10561457A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1056 10561530A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1056 10561535A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1056 10561536A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1056 10561568A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1056 10561624A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1056 10561631A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1056 10561631A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1057 10571213A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1057 10571214A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1057 10571350A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1057 10571360A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1066 10661286A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1068 10681103A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1071 10711003A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1071 10711003A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1071 10711007A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1071 10711012A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1071 10711024A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1071 10711024A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1071 10711090A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1071 10711146A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1071 10711154A0 IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1071 10711154A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1071 10711154A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1071 10711158A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1071 10711177A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1071 10711186A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1071 10711188A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-19.C4591001IEC4591001 1071 10711213A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07AC4591001IEC4591001 1073 10731070A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1073 10731089A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1073 10731099A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1073 10731102A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1073 10731119A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1073 10731126A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1077 10771032A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1077 10771066A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1077 10771103A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1077 10771207A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1077 10771224A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1077 10771225A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1077 10771230A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1077 10771252A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1079 10791064A EX09A05Phase 1 only: Individuals with a history of autoimmune disease or an active autoimmune disease requiring therapeutic intervention EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1079 10791069A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1079 10791088A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1079 10791095A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1079 10791269A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1079 10791292A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1080 10801097A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1080 10801174A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1081 10811083A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1081 10811183A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1082 10821030A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1082 10821046A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1082 10821091A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1082 10821092A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1082 10821144A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1082 10821191A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1082 10821200A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1082 10821206A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1082 10821222A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-30.C4591001IEC4591001 1083 10831028A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1083 10831030A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1083 10831037A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1083 10831038A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1083 10831048A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1083 10831049A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1083 10831058A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1083 10831063A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1083 10831087A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1083 10831088A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1083 10831109A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1083 10831126A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1083 10831131A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1083 10831135A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1083 10831150A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1083 10831151A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1083 10831177A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1083 10831180A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1083 10831193A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1083 10831196A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1083 10831202A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1083 10831211A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1083 10831238A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1083 10831246A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1083 10831258A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1083 10831260A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1083 10831284A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 OPEN LABEL TREATMENT2021-03-02B„C4591001IEC4591001 1084 10841086A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1084 10841094A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1084 10841094A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1084 10841105A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1084 10841124A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1084 10841143A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1084 10841179A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1084 10841224A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1084 10841237A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1084 10841257A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1084 10841263A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1084 10841354A EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1084 10841360A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1084 10841412A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1084 10841487A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1084 10841534A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1084 10841554A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-21.C4591001IEC4591001 1084 10841585A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-08.C4591001IEC4591001 1085 10851020A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-01.C4591001IEC4591001 1085 10851030A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1085 10851106A EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1085 10851154A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1085 10851192A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1087 10871097A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1087 10871321A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1087 10871451A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1087 10871488A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1087 10871511A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1087 10871512A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22AC4591001IEC4591001 1087 10871598A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1088 10881209A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1089 10891010A016EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1089 10891010A 13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1089 10891010A8 EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1089 10891036A4 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1089 10891040A4 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1089 10891041A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1089 10891112A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12AC4591001IEC4591001 1090 10901025A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1090 10901028A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1090 10901040A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1090 10901041A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1090 10901053A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1090 10901054A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1090 10901055A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1090 10901084A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1090 10901085A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1090 10901093A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1090 10901120A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1090 10901128A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1090 10901199A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1090 10901211A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1090 10901221A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1090 10901224A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1090 10901225A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1090 10901238A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1090 10901246A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1090 10901248A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1090 10901250A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1090 10901276A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1090 10901324A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1090 10901333A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1090 10901447A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1090 10901453A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1090 10901512A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1090 10901515A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1090 10901522A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1090 10901561A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1090 10901567A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-30.C4591001IEC4591001 1091 10911009A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1091 10911056A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1091 10911086A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1091 10911089A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1091 10911124A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1091 10911136A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1091 10911158A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1091 10911204A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1091 10911212A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1091 10911216A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1091 10911278A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1091 10911278A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1091 10911329A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1092 10921090A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1092 10921102A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1092 10921104A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1092 10921190A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1093 10931004A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1093 10931008A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1093 10931015A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1093 10931055A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25AC4591001IEC4591001 1093 10931060A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-09B¨C4591001IEC4591001 1093 10931079A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1093 10931082A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1093 10931104A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1093 10931105A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1093 10931142A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1093 10931153A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1093 10931154A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1093 10931161A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1093 10931164A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1093 10931165A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1093 10931166A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1093 10931167A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1093 10931172A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1093 10931176A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1093 10931206A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1093 10931207A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1093 10931213A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1093 10931220A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1093 10931221A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1093 10931225A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1094 10941020A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1094 10941038A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1094 10941113A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1094 10941185A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1094 10941190A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-30.C4591001IEC4591001 1094 10941191A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-30AC4591001IEC4591001 1095 10951041A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1095 10951063A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1095 10951064A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1095 10951115A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1095 10951120A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1095 10951187A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1095 10951193A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1095 10951235A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1095 10951237A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1095 10951240A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1095 10951246A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1095 10951273A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1095 10951275A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1095 10951287A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1095 10951289A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1095 10951297A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1095 10951302A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1095 10951303A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1096 10961009A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1096 10961036A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-03-02BÆC4591001IEC4591001 1096 10961036A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-03-02BÆC4591001IEC4591001 1096 10961106A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1096 10961107A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1096 10961108A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1096 10961116A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1096 10961153A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1096 10961228A IN04A07Capable of giving personal signed informed consent/have parent/legal guardian capable of giving signed informed consent, which includes compliance with requirements, restrictions in ICD and protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1096 10961263A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1096 10961263A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1096 10961296A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1096 10961310A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1096 10961380A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1096 10961389A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1097 10971003A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19AC4591001IEC4591001 1097 10971040A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1097 10971107A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08AC4591001IEC4591001 1098 10981090A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1098 10981104A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1098 10981114A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1098 10981115A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1098 10981155A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14AC4591001IEC4591001 1098 10981162A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14AC4591001IEC4591001 1098 10981168A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-15AC4591001IEC4591001 1098 10981169A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-15AC4591001IEC4591001 1098 10981264A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1101 11011019A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1101 11011023A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1101 11011077A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-18AC4591001IEC4591001 1101 11011117A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1107 11071002A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-29.C4591001IEC4591001 1107 11071017A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1107 11071051A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1107 11071058A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1107 11071066A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1107 11071081A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1107 11071088A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1107 11071095A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1107 11071100A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1107 11071101A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1107 11071120A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1107 11071141A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1107 11071142A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1107 11071161A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1107 11071177A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1107 11071198A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1107 11071218A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1107 11071220A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1107 11071221A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1109 11091259A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-16AC4591001IEC4591001 1109 11091339A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1109 11091349A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28AC4591001IEC4591001 1109 11091357A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1110 11101094A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1110 11101105A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1110 11101114A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1110 11101257A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1110 11101265A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1110 11101370A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1111 11111098A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1111 11111119A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1112 11121022A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1112 11121061A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1112 11121080A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1112 11121178A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1112 11121206A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1112 11121251A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1112 11121320A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1112 11121336A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1114 11141026A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1114 11141073A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1114 11141127A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1116 11161015A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26AC4591001IEC4591001 1116 11161018A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1116 11161040A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1116 11161050A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1116 11161069A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1116 11161078A EX19A05Phase 1 only: Positive test for HIV, hepatitis B surface antigen (HBsAg), hepatitis B core antibodies (HBc Abs), or hepatitis C virus antibodies (HCV Abs) at screening visit EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1116 11161174A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1116 11161211A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1116 11161211A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1116 11161223A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1116 11161223A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1116 11161242A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1116 11161304A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1117 11171016A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1117 11171036A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-01-28B¢C4591001IEC4591001 1117 11171036A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-01-28B¢C4591001IEC4591001 1117 11171044A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1117 11171049A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1117 11171054A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1117 11171057A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1117 11171060A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1117 11171080A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1117 11171094A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1117 11171106A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1117 11171112A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1117 11171117A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1117 11171118A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1117 11171128A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1117 11171130A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1117 11171149A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1117 11171186A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-01BwC4591001IEC4591001 1117 11171186A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-01BwC4591001IEC4591001 1120 11201004A4 EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-29.C4591001IEC4591001 1120 11201009A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1120 11201011A11EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1120 11201022A8 EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1120 11201026A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1120 11201038A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04AC4591001IEC4591001 1120 11201040A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1120 11201041A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1120 11201046A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1120 11201075A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1120 11201089A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1120 11201094A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1120 11201107A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1120 11201111A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1120 11201123A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1120 11201132A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1120 11201136A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1120 11201145A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1120 11201151A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1120 11201153A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1120 11201156A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1120 11201166A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201173A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201175A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201178A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201179A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201180A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201184A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1120 11201187A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1120 11201188A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1120 11201190A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1120 11201199A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1120 11201204A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1120 11201209A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1120 11201219A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1120 11201232A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1120 11201233A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1120 11201239A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1120 11201257A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1120 11201263A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1120 11201267A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1120 11201268A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1120 11201271A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1120 11201272A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1120 11201282A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1120 11201304A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1120 11201309A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1120 11201312A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1120 11201314A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1120 11201324A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1120 11201332A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1120 11201344A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1120 11201354A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1120 11201365A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1120 11201366A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1120 11201370A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1120 11201373A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1120 11201376A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1120 11201381A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1120 11201385A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1120 11201391A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1120 11201396A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1120 11201401A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1120 11201402A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1120 11201429A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1120 11201436A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-30AC4591001IEC4591001 1121 11211048A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1121 11211089A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1122 11221006A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03AC4591001IEC4591001 1122 11221022A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1122 11221036A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1122 11221056A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1123 11231004A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1123 11231024A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1123 11231032A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1123 11231125A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1123 11231150A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1123 11231174A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1123 11231174A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1123 11231227A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1123 11231301A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24AC4591001IEC4591001 1123 11231343A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1123 11231363A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1123 11231370A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1123 11231396A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1123 11231424A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-01.C4591001IEC4591001 1123 11231444A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-09.C4591001IEC4591001 1124 11241237A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-14.C4591001IEC4591001 1125 11251003A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1125 11251008A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1125 11251011A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1125 11251013A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1125 11251026A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1125 11251042A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1125 11251046A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1125 11251052A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1125 11251060A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1125 11251074A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1125 11251090A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1125 11251111A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1125 11251116A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1125 11251122A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1125 11251164A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1125 11251172A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1125 11251188A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1125 11251205A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1125 11251216A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1125 11251217A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1125 11251233A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1125 11251235A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1125 11251245A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-09.C4591001IEC4591001 1126 11261272A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-14.C4591001IEC4591001 1127 11271013A15EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1127 11271063A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1127 11271066A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1127 11271091A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1127 11271103A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1127 11271113A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1128 11281065A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1128 11281069A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1128 11281136A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1128 11281180A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1128 11281254A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1128 11281290A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1128 11281310A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1128 11281361A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1128 11281369A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1129 11291048A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04AC4591001IEC4591001 1129 11291082A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-10AC4591001IEC4591001 1129 11291117A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17AC4591001IEC4591001 1129 11291124A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1129 11291144A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1129 11291156A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1129 11291169A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1129 11291208A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-29.C4591001IEC4591001 1129 11291235A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1129 11291253A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1129 11291259A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-11-19.C4591001IEC4591001 1131 11311006A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1131 11311060A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1131 11311066A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1131 11311074A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1131 11311077A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1131 11311096A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1131 11311098A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1131 11311105A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1131 11311108A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1131 11311121A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1131 11311122A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1131 11311127A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1131 11311128A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1131 11311135A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1131 11311146A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1131 11311155A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1131 11311189A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1131 11311191A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1131 11311202A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1131 11311203A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1131 11311212A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1131 11311231A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1131 11311234A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1131 11311234A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1131 11311240A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1131 11311240A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1131 11311242A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1131 11311242A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1131 11311248A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1131 11311250A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1131 11311261A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-30.C4591001IEC4591001 1131 11311284A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-23.C4591001IEC4591001 1133 11331017A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1133 11331032A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1133 11331035A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1133 11331049A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1133 11331053A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1133 11331061A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1133 11331065A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1133 11331078A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1133 11331101A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-08.C4591001IEC4591001 1133 11331109A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-08.C4591001IEC4591001 1133 11331112A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-08.C4591001IEC4591001 1133 11331181A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1133 11331224A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1133 11331225A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1133 11331245A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1133 11331260A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1133 11331310A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1133 11331311A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1133 11331331A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1133 11331353A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1133 11331382A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02AC4591001IEC4591001 1133 11331390A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1133 11331405A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09AC4591001IEC4591001 1133 11331405A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 OPEN LABEL TREATMENT2021-01-22BˆC4591001IEC4591001 1133 11331436A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1133 11331442A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1133 11331458A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1133 11331482A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1133 11331493A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1133 11331494A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1133 11331514A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 1133 11331520A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1133 11331520A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1133 11331576A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331597A IN01A07Male or female participants between 18 and 55 years inclusive and 65 and 85 years inclusive (Phase 1) or >= 12 years (Phase 2/3) at randomization. Participants <18 years cannot be enrolled in EU INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331599A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331607A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331608A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331611A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331620A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1133 11331623A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1134 11341003A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1134 11341009A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1134 11341049A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1134 11341067A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13AC4591001IEC4591001 1134 11341090A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1134 11341141A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1134 11341150A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1134 11341189A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1134 11341191A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1134 11341223A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1134 11341267A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1134 11341272A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1134 11341329A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1134 11341376A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1134 11341383A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1134 11341391A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1134 11341427A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1135 11351010A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1135 11351034A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1135 11351056A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1135 11351066A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1135 11351066A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1135 11351089A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1135 11351107A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1135 11351133A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1135 11351140A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1135 11351141A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1135 11351209A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1135 11351271A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1135 11351272A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1135 11351302A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1135 11351305A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1135 11351318A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1135 11351329A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1135 11351340A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1135 11351352A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1135 11351357A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16AC4591001IEC4591001 1135 11351358A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1135 11351385A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-19.C4591001IEC4591001 1135 11351386A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-19.C4591001IEC4591001 1135 11351397A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1135 11351406A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1135 11351419A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1135 11351447A IN01A06Male or female participants between the ages of 18 and 55 years, inclusive, and 65 and 85 years, inclusive (Phase 1), or >= 16 years (Phase 2/3), at randomization INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1135 11351478A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1135 11351481A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1135 11351507A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1135 11351570A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1136 11361005A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1136 11361022A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1136 11361025A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1136 11361061A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1136 11361068A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1136 11361069A EX05A07Previous clinical (based on COVID-19 symptoms/signs alone if no SARS-CoV-2 NAAT result) or microbiological (based on COVID-19 symptoms/signs and positive SARS-CoV-2 NAAT result) diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1136 11361071A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1139 11391022A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1139 11391036A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1139 11391046A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1139 11391064A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1139 11391123A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1139 11391123A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1139 11391176A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-17.C4591001IEC4591001 1139 11391184A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-18.C4591001IEC4591001 1139 11391194A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-21.C4591001IEC4591001 1139 11391234A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-05.C4591001IEC4591001 1140 11401038A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1140 11401076A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-07.C4591001IEC4591001 1140 11401095A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1140 11401098A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1140 11401103A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1140 11401105A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1140 11401120A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1140 11401120A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1140 11401122A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1140 11401128A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1140 11401139A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1140 11401162A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1140 11401192A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1140 11401196A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1140 11401205A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1140 11401212A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1140 11401221A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1140 11401229A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1140 11401234A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1140 11401253A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1140 11401295A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1140 11401296A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1140 11401339A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-18.C4591001IEC4591001 1140 11401341A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-21.C4591001IEC4591001 1140 11401342A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-21.C4591001IEC4591001 1140 11401355A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-23.C4591001IEC4591001 1140 11401360A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-28.C4591001IEC4591001 1140 11401368A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-29.C4591001IEC4591001 1141 11411002A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1141 11411035A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1141 11411095A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1141 11411126A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1141 11411150A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1141 11411261A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1142 11421024A16EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31.C4591001IEC4591001 1142 11421039A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1142 11421076A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1142 11421076A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1142 11421080A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1142 11421080A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1142 11421087A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1142 11421088A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1142 11421088A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1142 11421144A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1142 11421147A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1142 11421170A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1142 11421170A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1142 11421186A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1142 11421186A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1142 11421241A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1142 11421246A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1142 11421291A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1142 11421381A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-28.C4591001IEC4591001 1142 11421382A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-12-28.C4591001IEC4591001 1142 11421387A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2021-01-04.C4591001IEC4591001 1145 11451035A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1145 11451045A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1145 11451048A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1145 11451092A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1145 11451105A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1146 11461003A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1146 11461006A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1146 11461008A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1146 11461014A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1146 11461029A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1146 11461032A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1146 11461047A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1146 11461048A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1146 11461099A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1146 11461105A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1146 11461115A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1146 11461121A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1146 11461131A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1146 11461134A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1146 11461213A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1146 11461217A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1146 11461257A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1146 11461330A IN01A06Male or female participants between the ages of 18 and 55 years, inclusive, and 65 and 85 years, inclusive (Phase 1), or >= 16 years (Phase 2/3), at randomization INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1146 11461362A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1146 11461383A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1146 11461396A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1147 11471002A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-07-30.C4591001IEC4591001 1147 11471005A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03.C4591001IEC4591001 1147 11471022A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1147 11471069A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1147 11471080A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1147 11471083A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1147 11471095A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1147 11471098A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1147 11471156A4 IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1147 11471161A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1147 11471172A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1147 11471214A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1147 11471215A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1147 11471248A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1149 11491002A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1149 11491003A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-05.C4591001IEC4591001 1149 11491032A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1149 11491038A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-10.C4591001IEC4591001 1149 11491111A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1149 11491240A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1149 11491291A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1149 11491336A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1150 11501042A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1150 11501108A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1150 11501109A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1152 11521028A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1152 11521055A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-13.C4591001IEC4591001 1152 11521232A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1152 11521300A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1156 11561017A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1156 11561017A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1156 11561027A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1156 11561168A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1156 11561169A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1156 11561232A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1157 11571025A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1157 11571028A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17AC4591001IEC4591001 1157 11571032A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1157 11571071A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1157 11571087A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1157 11571107A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1157 11571122A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1161 11611002A22EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31AC4591001IEC4591001 1161 11611008A22EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-07-31AC4591001IEC4591001 1161 11611011A22EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-01AC4591001IEC4591001 1161 11611014A22EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-01AC4591001IEC4591001 1161 11611018A22EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-01AC4591001IEC4591001 1161 11611023A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-03AC4591001IEC4591001 1162 11621024A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-04AC4591001IEC4591001 1162 11621092A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1162 11621231A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1162 11621232A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1162 11621317A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1162 11621318A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1162 11621319A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1162 11621424A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1162 11621453A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1162 11621461A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1162 11621477A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30AC4591001IEC4591001 1162 11621478A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1162 11621503A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1162 11621506A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1162 11621517A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1162 11621577A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1163 11631022A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-04.C4591001IEC4591001 1163 11631047A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-06.C4591001IEC4591001 1163 11631090A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1163 11631119A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1166 11661101A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1166 11661101A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1167 11671003A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14AC4591001IEC4591001 1167 11671072A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1167 11671156A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1167 11671227A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1168 11681238A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1170 11701365A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22AC4591001IEC4591001 1171 11711035A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1171 11711150A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1171 11711238A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1174 11741054A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1174 11741068A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1174 11741070A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1178 11781038A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1178 11781056A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31AC4591001IEC4591001 1178 11781083A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1178 11781317A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1179 11791048A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1185 11851006A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-27AC4591001IEC4591001 1185 11851026A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-27.C4591001IEC4591001 1194 11941070A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1194 11941104A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1203 12031019A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1203 12031023A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1203 12031035A IN05A06Phase 2/3 only: Participants who, in the judgment of the investigator, are at higher risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1203 12031036A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1203 12031046A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1203 12031049A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1203 12031052A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1203 12031062A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1203 12031065A IN05A05Participants who, in the judgment of the investigator, are at risk for acquiring COVID-19 INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1203 12031070A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-26.C4591001IEC4591001 1204 12041085A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1204 12041114A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1204 12041148A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1204 12041156A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1204 12041160A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1204 12041180A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1204 12041183A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1204 12041207A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1204 12041232A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1204 12041277A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1204 12041278A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1204 12041278A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-21.C4591001IEC4591001 1207 12071045A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-01-26BUC4591001IEC4591001 1212 12121023A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-03AC4591001IEC4591001 1218 12181029A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-19.C4591001IEC4591001 1218 12181029A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-19.C4591001IEC4591001 1218 12181029A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-11-19.C4591001IEC4591001 1219 12191019A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1219 12191061A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-08.C4591001IEC4591001 1220 12201001A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1220 12201001A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1220 12201002A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1220 12201002A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1220 12201005A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1220 12201007A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-29.C4591001IEC4591001 1220 12201010A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1220 12201011A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1220 12201019A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1220 12201023A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1220 12201023A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-19.C4591001IEC4591001 1220 12201064A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-01.C4591001IEC4591001 1220 12201064A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-12-01.C4591001IEC4591001 1221 12211008A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-15.C4591001IEC4591001 1221 12211019A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-29.C4591001IEC4591001 1221 12211034A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-11-16.C4591001IEC4591001 1221 12211035A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-11-16.C4591001IEC4591001 1221 12211060A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-11-24.C4591001IEC4591001 1223 12231002A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1223 12231071A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1223 12231092A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1223 12231093A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-02.C4591001IEC4591001 1223 12231110A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1223 12231165A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1223 12231167A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1223 12231168A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1223 12231169A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1223 12231169A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-14.C4591001IEC4591001 1223 12231185A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1223 12231191A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1223 12231200A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21AC4591001IEC4591001 1223 12231217A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1223 12231250A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16AC4591001IEC4591001 1223 12231282A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2021-01-09.C4591001IEC4591001 1224 12241157A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16AC4591001IEC4591001 1224 12241158A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18AC4591001IEC4591001 1226 12261109A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1226 12261260A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1226 12261265A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1226 12261749A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1226 12261782A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1226 12261804A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1226 12261808A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-17.C4591001IEC4591001 1226 12262101A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1226 12262132A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-16BƒC4591001IEC4591001 1229 12291039A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1229 12291053A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1229 12291053A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1229 12291090A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-02.C4591001IEC4591001 1229 12291128A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1229 12291132A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1229 12291135A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-18B‡C4591001IEC4591001 1229 12291161A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1229 12291199A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1229 12291199A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-13.C4591001IEC4591001 1230 12301013A IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1230 12301042A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-26.C4591001IEC4591001 1230 12301061A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1230 12301061A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1230 12301081A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1230 12301088A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1230 12301090A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1230 12301093A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1230 12301126A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1230 12301131A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1230 12301149A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1230 12301156A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1230 12301160A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1230 12301180A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1230 12301194A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-08.C4591001IEC4591001 1231 12311048A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1231 12311066A03 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1231 12311066A 3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1231 12311066A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-11.C4591001IEC4591001 1231 12311086A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-12.C4591001IEC4591001 1231 12311088A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-12AC4591001IEC4591001 1231 12311192A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1231 12311305A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311332A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311345A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311369A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311378A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311406A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311406A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311453A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-15.C4591001IEC4591001 1231 12311562A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-16.C4591001IEC4591001 1231 12311622A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-16.C4591001IEC4591001 1231 12311739A8 EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1231 12311805A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1231 12311867A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1231 12311885A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18AC4591001IEC4591001 1231 12311902A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12311919A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312017A@3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312017A013EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312017A 2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312017A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312099A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312147A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1231 12312189A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312222A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19AC4591001IEC4591001 1231 12312238A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312246A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312353A8 EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312386A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1231 12312404A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312437A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1231 12312480A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1231 12312483A4 EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20AC4591001IEC4591001 1231 12312555A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1231 12312736A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12312821A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12312839A16EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12312942A 3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12312942A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12312981A3 EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-21.C4591001IEC4591001 1231 12313140A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-02-25B¼C4591001IEC4591001 1231 12313142A3 IN03A00Healthy participants who are determined by medical history, physical examination, and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1231 12313144A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1231 12313146A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1231 12313240A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1231 12313299A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-22.C4591001IEC4591001 1231 12313333A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313341A 13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313341A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313373A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313392A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313451A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-23.C4591001IEC4591001 1231 12313812A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12313820A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12313857A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12313885A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12313985A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12313985A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12314052A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12314056A EX14A00Receipt of blood/plasma products or immunoglobulin, from 60 days before study intervention administration or planned receipt throughout the study EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25.C4591001IEC4591001 1231 12314127A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1231 12314253A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1231 12314341A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1231 12314390A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314401A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYG0ÛÃV101_VAX3 REPEAT SCREENING 1 2021-01-15BŽC4591001IEC4591001 1231 12314487A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314538A@ IN04A00Capable of giving personal signed informed consent, which includes compliance with the requirements and restrictions listed in the ICD and in this protocol INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314538A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314538A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314538A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314608A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314609A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1231 12314729A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12314733A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12314949A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12314956A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12314975A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12314990A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12315028A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-28.C4591001IEC4591001 1231 12315212A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1231 12315227A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1231 12315243A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1231 12315346A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1231 12315367A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1231 12315395A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-30.C4591001IEC4591001 1231 12315570A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1231 12315608A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31AC4591001IEC4591001 1232 12321021A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1232 12321037A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-18AC4591001IEC4591001 1232 12321212A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1232 12321245A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-11.C4591001IEC4591001 1232 12321261A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1232 12321295A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1232 12321432A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-28AC4591001IEC4591001 1235 12351018A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1235 12351021A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1235 12351042A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-08.C4591001IEC4591001 1235 12351051A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1235 12351164A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1235 12351167A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-09AC4591001IEC4591001 1241 12411121A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-14.C4591001IEC4591001 1241 12411169A2 IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1241 12411202A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-17.C4591001IEC4591001 1241 12411304A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-19.C4591001IEC4591001 1241 12411434A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-24.C4591001IEC4591001 1241 12411525A2 EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1241 12411533A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1241 12411597A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-03.C4591001IEC4591001 1241 12411652A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-04.C4591001IEC4591001 1241 12411737A13EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1241 12411738A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-16.C4591001IEC4591001 1241 12412011A1 EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 1241 12412068A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1241 12412234A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1241 12412234A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1241 12412265A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1241 12412292A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-16.C4591001IEC4591001 1241 12412388A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1241 12412481A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-22.C4591001IEC4591001 1241 12412531A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-23.C4591001IEC4591001 1246 12461016A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-26.C4591001IEC4591001 1246 12461042A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1246 12461054A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-01.C4591001IEC4591001 1246 12461062A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-02.C4591001IEC4591001 1246 12461064A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1246 12461083A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1246 12461091A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1246 12461101A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1246 12461102A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1246 12461125A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-09.C4591001IEC4591001 1246 12461141A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-12.C4591001IEC4591001 1247 12471024A IN01A05Male or female participants between the ages of 18 and 55 years, inclusive, 65 and 85 years, inclusive, or 18 and 85 years, inclusive, at randomization (dependent upon study phase) INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-24.C4591001IEC4591001 1247 12471065A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1247 12471072A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-28.C4591001IEC4591001 1247 12471097A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-29.C4591001IEC4591001 1247 12471129A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-30.C4591001IEC4591001 1247 12471169A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-05.C4591001IEC4591001 1247 12471191A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1247 12471192A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1247 12471195A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-06.C4591001IEC4591001 1247 12471207A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1247 12471207A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-07.C4591001IEC4591001 1248 12481079A0 IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1248 12481079A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1248 12481079A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-05.C4591001IEC4591001 1248 12481108A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-29.C4591001IEC4591001 1248 12481109A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1248 12481111A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1248 12481111A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1248 12481152A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-13.C4591001IEC4591001 1248 12481152A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-13.C4591001IEC4591001 1248 12481222A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-20.C4591001IEC4591001 1248 12481223A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-20.C4591001IEC4591001 1248 12481236A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1248 12481239A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1248 12481242A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 1248 12481251A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-20.C4591001IEC4591001 1251 12511012A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1251 12511017A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-20.C4591001IEC4591001 1251 12511050A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-25AC4591001IEC4591001 1251 12511064A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1251 12511142A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1251 12511144A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1251 12511174A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-15.C4591001IEC4591001 1251 12511202A IN02A00Participants who are willing and able to comply with all scheduled visits, vaccination plan, laboratory tests, lifestyle considerations, and other study procedures INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1251 12511266A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-28.C4591001IEC4591001 1252 12521013A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-18.C4591001IEC4591001 1254 12541118A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-10.C4591001IEC4591001 1254 12541161A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-18.C4591001IEC4591001 1254 12541186A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-14.C4591001IEC4591001 1254 12541205A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-24.C4591001IEC4591001 1254 12541206A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-10-24.C4591001IEC4591001 1254 12541212A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-24.C4591001IEC4591001 1254 12541213A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-10-24.C4591001IEC4591001 1260 12601028A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-08-31.C4591001IEC4591001 1260 12601049A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-02AC4591001IEC4591001 1261 12611004A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1264 12641207A IN03A06Healthy participants, determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for the study. Specific criteria apply for HIV/HCV/HBVINCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 1265 12651009A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-26.C4591001IEC4591001 1265 12651017A EX12A00Previous vaccination with any coronavirus vaccine EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-08-27.C4591001IEC4591001 1265 12651036A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01.C4591001IEC4591001 1265 12651077A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-09.C4591001IEC4591001 1265 12651164A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23AC4591001IEC4591001 1269 12691090A EX04A00Receipt of medications intended to prevent COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-01AC4591001IEC4591001 4444 44441047A EX10A00Bleeding diathesis or condition associated with prolonged bleeding that would, in the opinion of the investigator, contraindicate intramuscular injection EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441128A EX11A00Women who are pregnant or breastfeeding EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441132A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441132A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441146A EX08A00Immunocompromised individuals with known or suspected immunodeficiency, as determined by history and/or laboratory/physical examination EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441246A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441250A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441250A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-21.C4591001IEC4591001 4444 44441339A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 4444 44441368A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 4444 44441537A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-22.C4591001IEC4591001 4444 44441609A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441609A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441622A EX05A05Previous clinical or microbiological diagnosis of COVID-19 EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441637A EX03A00History of severe adverse reaction associated with a vaccine and/or severe allergic reaction (eg, anaphylaxis) to any component of the study intervention(s) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441687A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441691A EX21A00Investigator site staff or Pfizer employees directly involved in the conduct of the study, site staff otherwise supervised by the investigator, and their respective family members EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441698A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441757A EX13A01Subjects who receive immunosuppressive therapy, such as cytotoxic agents or systemic corticosteroids EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-23.C4591001IEC4591001 4444 44441814A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 4444 44441866A EX15A00Participation in other studies involving study intervention within 28 days prior to study entry and/or during study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 4444 44441882A IN03A05Healthy participants who are determined by medical history, physical examination (if required), and clinical judgment of the investigator to be eligible for inclusion in the study INCLUSIONNNDí]V1_DAY1_VAX1_L SCREENING 2020-09-25.C4591001IEC4591001 4444 44442099A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-27.C4591001IEC4591001 4444 44442185A EX01A00Other medical or psychiatric condition incl. recent (within past year) or active suicidal ideation/behavior/lab abnormality that may increase the risk of study participation EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-27.C4591001IEC4591001 4444 44442231A EX02A00Known infection with human immunodeficiency virus (HIV), hepatitis C virus (HCV), or hepatitis B virus (HBV) EXCLUSIONYYDí]V1_DAY1_VAX1_L SCREENING 2020-09-27.